• 2011- , Associate Professor, USTC.

Education

• 2006-2010, Post-doc., Medical Informatics & Bioinformatics, Yale University.
• 2005, Ph.D., Biomedical Engineering (major in Bioinformatics), USTC.
• 2000, B.S., Biology Sciences (major in Biophysics), USTC.

Teaching

• Spring 2012, “Fundamentals of Biological Science and Medical Engineering”
• Spring 2012, “Topics in Biomedical Engineering”
• Fall 2011, “Introduction to Bioinformatics Algorithms”

Research Interests

• Bioinformatics and Systems Biology
• Biomedical Information Processing
• Machine Learning and Data Mining
• Human Computer Interaction

Selected Publications

1.      Liu,Y., Wang,M., Feng,H., Li.A.* A novel CNA/LOH detection algorithm using normal-tumor SNP-array data. Accepted by ICBBE 2012 (*corresponding author)

2.      Li,A.*, Liu,Z.*, Lezon-Geyda,K., Sarkar,S., Lannin,D., Schulz,V., Krop,I., Winer,E., Harris,L., Tuck,D. (2011) GPHMM: an integrated hidden Markov model for identification of copy number alteration and loss of heterozygosity in complex tumor samples using whole genome SNP arrays. Nucleic Acids Research, 39(12):4928-41. (* joint first author)

3.      Liu,Z.*, Li,A.*, Schulz,V., Tuck,D.P. (2010) MixHMM: Infering Copy Number Variation and Allelic Imbalance using SNP Arrays and Tumor Samples Mixed with Stromal Cells. PLoS ONE, 5(6): e10909. (* joint first author)

4.      Li,A., Tuck,D.P. (2009) An Effective Tri-Clustering Algorithm Combining Expression Data with Gene Regulation Information. Gene Regulation and Systems Biology, 3: 49–64.

5.      Xiang,B., Li,A., Valentin,D., Nowak,N.J., Zhao,H., Li,P.. (2008) Analytical and clinical validity of whole-genome oligonucleotide array comparative genomic hybridization for pediatric patients with mental retardation and developmental delay. Am. J. Med. Genet. A., 146A(15):1942-54.

6.      Sung,LY., Gao,S., Shen,H., Yu,H., Song,Y., Smith,SL., Chang,CC., Inoue,K., Kuo,L., Lian,J., Li,A., Tian,XC., Tuck,DP., Weissman,SM., Yang,X., Cheng,T. (2006) Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer. Nature Genetics, 38(11):1323-8.

7.      Li,A.*, Xue,Y.*, Jin,C., Wang,M. and Yao,X. (2006) Prediction of Nepsilon- acetylation on internal lysines implemented in Bayesian Discriminant Method. Biochem. Biophys. Res. Commun., 350(4): 818-24. (* joint first author)

8.      Xue,Y.*, Li,A.*, Wang,L., Feng,H. and Yao,X. (2006) PPSP: Prediction of PK-specific phosphorylation site with Bayesian decision theory. BMC bioinformatics. 7:163. (* joint first author)

9.      Wang,X., Li,A., Jiang,Z. and Feng,H. (2006) Missing value estimation for DNA microarray gene expression data by Support Vector Regression imputation and orthogonal coding scheme. BMC bioinformatics, 7:32.

10.   Xie,D.*, Li,A.*, Wang,M., Fan,Z. and Feng,H. (2005) LOCSVMPSI: a web server for subcellular localization for eukaryotic proteins using SVM and profile of PSI-BLAST. Nucleic Acids Research. 33 (Web Server issue): W105-10. (* joint first author)

11.   Li,A., Wang,L., Shi,Y., Wang,M., Jiang,Z. and Feng,H. (2005) Phosphorylation Site Prediction with A Modified k-Nearest Neighbor Algorithm and BLOSUM62 Matrix. 27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, p6075-8.