Welcome to the homepage of ZHANG-LAB. The major research interest of Dr. Huafeng Zhang is to decipher molecular basis underlying hypoxia and HIF (Hypoxic-inducible-factor) -mediated tumorigenesis and tumor metabolism,including but not limited to glucose and lipid metabolism,mitochondria respiration and epigenetic modification. Apart from mechanistic studies, screening for HIF-specific inhibitors for cancer therapy is also under way in our lab.
Main research interests:
1. Tumor microenvironment and tumor metabolism
2. Molecular mechanism of tumor metastasis
3. Epigenetics and tumor development
4. Screening and development of new anti-tumor drugs