Jinming Hu, Ph.D., Professor


CAS Key Laboratory of Soft Matter Chemistry,

Hefei National Laboratory for Physical Sciences at the Microscale,

Department of Polymer Science and Engineering,

University of Science and Technology of China,

96 Jinzhai Rd, Hefei, Anhui 230026

Tel: +86-551-63607579


 


 

Professional Experience

Professor8/2017-Present

CAS Key Laboratory of Soft Matter Chemistry,

Hefei National Laboratory for Physical Sciences at the Microscale,

Department of Polymer Science and Technology of China,

University of Science and Technology of China

 

Research Professor, 1/2016-7/2017

CAS Key Laboratory of Soft Matter Chemistry,

Department of Polymer Science and Technology of China,

University of Science and Technology of China.

 

Postdoctoral Research Fellow (with Prof. Thomas P. Davis), 7/2013-12/2015

ARC Centre of Excellence in Convergent Bio-Nano Science & Technology,

The Monash Institute of Pharmaceutical Sciences,

Monash University, Australia.

 

Postdoctoral Research Associate (with Prof. Thomas P. Davis), 1/2013-7/2013

Australian Center for Nanomedicine,

Department of Chemical Engineering,

University of New South Wales, Australia.

 

Education Experience

Ph.D. 2007.9-2012.12 (Advisor: Prof. Shiyong Liu)

CAS Key Laboratory of Soft Matter Chemistry,

Department of Polymer Science and Engineering,

University of Science and Technology of China, Hefei, China

 

B.S. 2003.9-2007.7

Department of Chemical Engineering,

Hefei University of Technology, Hefei, China

 

Selected Honors and Awards

1.         National Science Foundation for Outstanding Young Scholars (2017)

2.         Thousand Talent Program for Young Outstanding Scientists2016

3.         Anhui Hundred Talent Program (2016)

4.         The First Prize of Anhui Province Natural Science Award in 2015 (ranking 2nd of 4 awardees)

5.         President Award for Excellent Graduate Students of Chinese Academy of Science (2012)

 

Professional Activity

1.         Editorial Board Member, Polymers

2.         Editorial Board Member, Current Gene Therapy

3.         Young Editorial Board Member, Chinese Chemical Letters

4.         Young Editorial Board Member, Journal of Functional Polymers (in Chinese)

 

Peer-Reviewed Publications (* Corresponding Authors; # co-first author)

Web of Science ResearcherID: F-2137-2011; ORCID ID: 0000-0002-6969-1343

(H-Index: 40, Total citations > 6300; Data from Google Scholar)

58      J. Cheng, G. H. Gan, Z. Q. Shen, L. Gao, G. Y. Zhang, J. M. Hu* “Red Light-Triggered Intracellular Carbon Monoxide Release Enables Selective Eradication of MRSA Infection” Angewandte Chemie International Edition, 2021, 10.1002/anie.202104024.

57       Y. T. Duan, K. W. He, G. Y. Zhang, J. M. Hu* “Photoresponsive Micelles Enabling Codelivery of Nitric Oxide and Formaldehyde for Combinatorial Antibacterial Applications” Biomacromolecules, 2021, 10.1021/

56       Y. T. Duan, M. Y. Zhang, Z. Q. Shen, M. D. Zhang, B. Zheng,* S. Cheng, J. M. Hu* “Photoresponsive Vesicles Enabling Sequential Release of Nitric Oxide (NO) and Gentamicin for Efficient Biofilm Eradication” Macromolecular rapid communications 2021, doi: 10.1002/marc.202000759 (Invited Contribution for the Special Issue of “Stimuli-responsive Polymers”).

55       S. Y. Tao,# J. Cheng#, G. Su, D. Li, Z. Q. Shen, F. H. Tao, T. You*, J. M. Hu* “" Breathing" Micelles for Combinatorial Treatment of Rheumatoid Arthritis” Angewandte Chemie International Edition, 2020, 59, 21864-21869 (VIP paper, Selected as Inside Cover, highlighted by Wileychem)

54       Z. L. Ding, K. W. He, Y. T. Duan, Z. Q. Shen, J. Cheng, G. Y. Zhang, J. M. Hu* “ Photo-degradable micelles for co-delivery of nitric oxide and doxorubicin” Journal of Materials Chemistry B, 2020, 31, 7009-7017. (Invited Contribution for Journal of Materials Chemistry B Emerging Investigators)

53       M. Y. Zhang, J Cheng, X. M. Huang, G. Y. Zhang, S. G. Ding,* J. M. Hu*, R. R. Qiao* “Photo-Degradable Micelles Capable of Releasing of Carbon Monoxide under Visible Light Irradiation”, Macromolecular rapid communications, 2020, 10.1002/marc.202000323.

52       Z. X. Ding, G. H. Liu*, J. M. Hu* “Ratiometric Fluorescent Mapping of pH and Glutathione Dictates Intracellular Transport Pathways of Micellar Nanoparticles” Biomacromolecules, 2020, 21, 3436-3446.

51        M. D. Zhang, R. R. Qiao,* J. M. Hu* “Engineering Metal-Organic Frameworks (MOFs) for Controlled Delivery of Physiological Gaseous Transmitters” Nanomaterials, 2020, 10, 1134.

50      M. Y. Zhang, J. Cheng, J. M. Hu* “Recent Advances on Macromolecular Nanovectors for Carbon Monoxide Delivery” Journal of Functional Polymers, 2020, 33421-432. (Invited Review Article, Selected as Front Cover, In Chinese)

49      Z. X. Ding, J. Cen, Y. Wu, K. Zhong, G. H. Liu, J. M. Hu*, S. Y. Liu* “Self-Immolative nanoparticles for stimuli-triggered activation, covalent trapping and accumulation of in situ generated small molecule theranostic fragments” Giant, 2020, 1, 100012.

48      J. Cheng, B. Zheng,* S. Cheng, G. Y. Zhang, J. M. Hu* “Metal-Free Carbon Monoxide-Releasing Micelles Undergo Tandem Photochemical Reactions for Cutaneous Wound Healing” Chemical Science, 2020, 11, 4499-4507. (Highlighted by InfoMat).

47       J. M. Hu*, S. Y. Liu “Fabrication of smart polymeric nanovectors to amplify intracellular oxidative stress for chemodynamic therapy” SCIENTIA SINICA Chimica 2020, 50 (3), 366-376 (in Chinese)

46      J. M. Hu, S. Y. Liu* “Autonomous Self-Healing to Combat Insulation Failure” Matter, 2020, 2, 288-289.

45       Y. T. Duan, Y. Wang, X. H. Li, G. Z. Zhang, G. Y. Zhang, J. M. Hu*Light-Triggered Nitric Oxide (NO) Release from Photoresponsive Polymersomes for Corneal Wound Healing” Chemical Science, 2020, 11, 186-194. (ISI Highly Cited Paper)

44      J. M. Hu*, S. Y. Liu* “Modulating intracellular oxidative stress via engineered nanotherapeutics” Journal of Controlled Release, 2020, 319, 333-343.

43      Y. H. Li, F. Y. Xin, J. M. Hu,* S. Jagdale, T. P. Davis, C. E. Hagemeyer, R. R. Qiao* “Functionalization of NaGdF4 nanoparticles with a dibromomaleimide-terminated polymer for MR/optical imaging of thrombosis” Polymer Chemistry, 2020, 11, 1010-1017.

42      Z. Q. Shen, K. W. He, Z. L. Ding, M. D. Zhang, Y. Q. Yu,* J. M. Hu* “Visible-Light-Triggered Self-Reporting Release of Nitric Oxide (NO) for Bacterial Biofilm Dispersal” Macromolecules, 2019, 52, 7668-7677.

41       Z. L. Ding, H. B. Sun, S. C. Ge, Y. Cai, Y. Yuan, Z. J. Hai, T. X. Tao, J. M. Hu,* B. Hu,* J. F. Wang,* G. L. Liang* “FurinControlled Fe3O4 Nanoparticle Aggregation and 19F Signal “TurnOn for Precise MR Imaging of Tumors” Advanced Functional Materials, 2019, 29, 1903860.

40      J. Cheng, K. W. He, S. Q. Shen, G. Y. Zhang, Y. Q. Yu,* J. M. Hu* “Nitric Oxide (NO)-Releasing Macromolecules: Rational Design and Biomedical Applications” Frontiers in Chemistry, 2019, 7, 530. (Invited Review Article)

39      K. N. Zhu, G. H. Liu, G. Y. Zhang, J. M. Hu,* S. Y. Liu* “Engineering Cross-Linkable Plasmonic Vesicles for Synergistic Chemo-Photothermal Therapy Using Orthogonal Light Irradiation” Macromolecules. 2018, 51, 8530.

38      J. M. Hu,* S. Y. Liu* “Recent advances on stimuli-responsive macromolecular magnetic resonance imaging (MRI) contrast agents” Science China Chemistry 2018, 61, 1110-1122.

37       Z. Q. Sun, G. H. Liu, J. M. Hu,* S. Y. Liu* “Photo-and reduction-responsive polymersomes for programmed release of small and macromolecular payloads” Biomacromolecules, 2018, 19, 2071-2081.

36      J. Y. Zhang, H. O. Zhou, H. Liu, J. M. Hu,* S. Y. Liu* “Fabrication of pHand Thermoresponsive ThreeLayered Micelles via HostGuest Interactions” Macromolecular rapid communications, 2018, 39, 1700225.

35       J. M. Hu, R. R. Qiao, M. R. Whittaker, J. F. Quinn, T. P. Davis* “Synthesis of star polymers by RAFT polymerization as versatile nanoparticles for biomedical applications” Australian Journal of Chemistry, 2017, 70, 1161-1170.

34      J. M. Hu,* S. Y. Liu* “Topological effects of macrocyclic polymers: from precise synthesis to biomedical applications” Science China Chemistry, 2017, 60, 1153-1161.

33       C. Wang, G. Y. Zhang, G. H. Liu,* J. M. Hu,* S. Y. Liu* “Photo-and thermo-responsive multicompartment hydrogels for synergistic delivery of gemcitabine and doxorubicin” Journal of Controlled Release, 2017, 259, 149-159.

32      K. N. Zhu, G. H. Liu, J. M. Hu,* S. Y. Liu* “Near-infrared light-activated photochemical internalization of reduction-responsive polyprodrug vesicles for synergistic photodynamic therapy and chemotherapy” Biomacromolecules, 2017, 18, 2571-2582.

31       K. N. Zhu, Z. Y. Deng, G. H. Liu*, J. M. Hu*, S. Y. Liu* "Photo-Regulated Cross-Linking of Superparamagnetic Iron Oxide Nanoparticle (SPION)-Loaded Hybrid Nanovectors with Synergistic Drug Release and Magnetic Resonance (MR) Imaging Enhancement", Macromolecules, 2017, 50, 1113-1125.

30      Z. Y. Deng, J. M. Hu*, S. Y. Liu* "Reactive Oxygen, Nitrogen, and Sulfur Species (RONSS)-Responsive Polymersomes for Triggered Drug Release", Macromolecular Rapid Communications, 2017, 38, 1600685 .

29          C. Z. Yao, X. R. Wang, G. H. Liu,* J. M. Hu,* S. Y. Liu* "Distinct Morphological Transitions of Photo-Reactive and Thermo-Responsive Vesicles for Controlled Release and Nanoreactors", Macromolecules, 2016, 49, 8282-8295.

28          J. M. Hu, M. R. Whittaker, J. F. Quinn,* T. P. Davis* “Nitric Oxide (NO) Endows Arylamine-Containing Block Copolymers with Unique Photoresponsive and Switchable LCST PropertiesMacromolecules 2016, 49, 2741–2749.

27           S. D. Tian, G. H. Liu, X. R. Wang, T. Wu, J. X. Yang, X. D. Ye, G. Y. Zhang, J. M. Hu,* S. Y. Liu* “pH-Regulated Reversible Transition Between Polyion Complexes (PIC) and Hydrogen Bonding Complexes (HBC) with Tunable Aggregation-Induced EmissionACS Applied Materials & Interfaces, 2016, 8, 3693-3702 (Invited Article in the "Applied Materials and Interfaces in China Forum" Special Issue).

26          S. D. Tian, G. H. Liu, X. R. Wang, G. Y. Zhang, J. M. Hu*pH-Responsive Tumor-Targetable Theranostic Nanovectors Based on Core Crosslinked (CCL) Micelles with Fluorescence and Magnetic Resonance (MR) DualImaging Modalities and Drug Delivery Performance”, Polymers, 2016, 8, 226. (Invited Article for the "Responsive Polymers for Drug Delivery, Imaging and Theranostic Functions" Special Issue; Selected as Front Cover)

25       J. M. Hu, S. Y. Liu*Supramolecular Assembly-Assisted Synthesis of Responsive Polymeric Materials with Controlled Chain Topologies”, Macromolecular Chemistry and Physics, 2015, 216, 591-604. Invited Trend Article. Chosen as one of "Best of Macromolecular Journals, Edition 2016". Yearly Most-accessed Article as of Oct, 2014-Sep, 2015.

24          L. Wang, G. H. Liu, X. R. Wang, J. M. Hu,* G. Y. Zhang,* S. Y. Liu*Acid-Disintegratable Polymersomes of pH-Responsive Amphiphilic Diblock Copolymers for Intracellular Drug DeliveryMacromolecules 2015, 48, 7262–7272. Monthly Most Read Article.

23          J. M. Hu, X. Wang, Y. F. Qian, Y. Q. Yu,* Y. Y. Jiang, G. Y. Zhang, S. Y. Liu*Cytoplasmic Reactive Cationic Amphiphiles for Efficient Intracellular Delivery and Self-Reporting Smart ReleaseMacromolecules, 2015, 48, 5959-5968.

22          J. M. Hu, M. R. Whittaker, S. H. Yu, J. F. Quinn,* T. P. Davis* Nitric Oxide (NO)-Cleavable Biomimetic Thermoresponsive Double Hydrophilic Diblock Copolymer with Tunable LCST”, Macromolecules, 2015, 48, 3817-3824.

21           J. M. Hu, M. R. Whittaker, T. P. Davis*, J. F. Quinn* “Application of Heterocyclic Polymers in the Ratiometric Spectrophotometric Determination of Fluoride”, ACS Macro Letters, 2015, 4, 236-241.

20          J. M. Hu, M. R. Whittaker, Y. Li, J. F. Quinn,* T. P. Davis* “The use of endogenous gaseous molecules (NO and CO2) to regulate the self-assembly of a dual-responsive triblock copolymer”, Polymer Chemistry, 2015, 6, 2407-2415.

19       J. M. Hu, G. Y. Zhang, Z. S. Ge, S. Y. Liu*Stimuli-Responsive Tertiary Amine Methacrylate-Based Block Copolymers: Synthesis, Supramolecular Self-Assembly and Functional Applications”, Progress in Polymer Science, 2014, 39, 1096–1143. Highly Cited Papers by Essential Science Indicators at ISI Web of Knowledge.

18       J. M. Hu, S. Y. Liu*Engineering Responsive Polymer Building Blocks with Host-Guest Molecular Recognition for Functional Applications”, Accounts of Chemical Research, 2014, 47, 2084-2095. Highly Cited Papers by Essential Science Indicators at ISI Web of Knowledge.

17            J. M. Hu, M. R. Whittaker, H. Doung, Y. Li, C. Boyer,* T. P. Davis* Biomimetic Polymers Responsive to a Biological Signaling Molecule: Nitric Oxide (NO) Triggered Reversible Self-assembly of Single Macromolecular Chains into Nanoparticles”, Angewandte Chemie International Edition, 2014, 53, 7779–7784.

16           J. M. Hu, G. H. Liu, T. Liu, C. Wang, G. Y. Zhang, S. Y. Liu*Spatiotemporal Monitoring Endocytic and Cytosolic pH Gradients with Endosomal Escaping pH-Responsive Micellar Nanocarriers”, Biomacromolecules, 2014, 15, 4293-4301.

15            X. L. Hu, J. M. Hu*, J. Tian, Z. S. Ge, G. Y. Zhang, K. F. Luo, S. Y. Liu* "Polyprodrug Amphiphiles: Hierarchical Assemblies for Shape-Regulated Cellular Internalization, Trafficking and Drug Delivery", Journal of the American Chemical Society, 2013, 135, 17617–17629. Highlighted by Science-Business eXchange doi:10.1038/scibx.2013.1366; Hot Papers by Essential Science Indicators at ISI Web of Knowledge. Highly Cited Papers by Essential Science Indicators at ISI Web of Knowledge.

14           Y. Li, T. Liu, Y. F. Qian, G. Y. Zhang, J. M. Hu,* and S. Y. Liu*Asymmetrically Functionalized β-Cyclodextrin-Based Star Copolymers for Integrated Gene Delivery and Magnetic Resonance Imaging Contrast Enhancement”, Polymer Chemistry, 2013, 5, 1743-1750.

13           J. M. Hu, T. Liu, G. Y. Zhang, F. Jin*, S. Y. Liu* “Synergistically Enhance Magnetic Resonance/Fluorescence Imaging Performance of Responsive Polymeric Nanoparticles under Mildly Acidic Biological Milieu”, Macromolecular Rapid Communications, 2013, 34, 749-758.

12       J. M. Hu, G. Q. Zhang*, S. Y. Liu* “Enzyme-Responsive Polymeric Assemblies, Nanoparticles and Hydrogels”, Chemical Society Reviews, 2012, 41, 5933-5949. Highly Cited Papers by Essential Science Indicators at ISI Web of Knowledge.

11            J. M. Hu, T. Wu, G. Y. Zhang, S. Y. Liu* "Efficient Synthesis of Single Gold Nanoparticle Hybrid Amphiphilic Triblock Copolymers and Their Controlled Self-Assembly", Journal of the American Chemical Society, 2012, 134, 7624–7627.

10           J. M. Hu, T. Wu, G. Q. Zhang*, S. Y. Liu*Highly Selective Fluorescence Sensing of Mercury Ions over a Broad Concentration Range Based on Mixed Polymeric Micelles”, Macromolecules, 2012, 45, 3939–3947.

9              J. M. Hu, Y. F. Qian,* X. F. Wang, T. Liu, S. Y. Liu* Drug-Loaded and Superparamagnetic Iron Oxide Nanoparticle Surface Embedded Amphiphilic Block Copolymer Micelles for Integrated Chemotherapeutic Drug Delivery and MR Imaging”, Langmuir, 2012, 28, 2073-2082.

8              J. M. Hu, G.Y. Zhang, Y. H. Geng*, S. Y. Liu* Micellar Nanoparticles of Coil-Rod-Coil Triblock Copolymers for Highly Sensitive and Ratiometric Fluorescent Detection of Fluoride Ions”, Macromolecules, 2011, 44, 8207–8214.

7               J. M. Hu, L. Dai, S. Y. Liu*Analyte-Reactive Amphiphilic Thermoresponsive Diblock Copolymer Micelles-Based Multifunctional Ratiometric Fluorescent Chemosensors”, Macromolecules, 2011, 44, 4699-4710.

6              J. M. Hu, X. Z. Zhang, D. Wang, X. L. Hu, T. Liu, G. Y. Zhang*, S. Y. Liu*Ultrasensitive Ratiometric Fluorescent pH and Temperature Probes Constructed from Dye-Labeled Thermoresponsive Double Hydrophilic Block Copolymers”, Journal of Materials Chemistry, 2011, 21, 19030-19038.

5               J. M. Hu, C. H. Li, Y. Cui, S. Y. Liu*Highly Selective Colorimetric and Fluorometric Probes for Fluoride Ions Based on Nitrobenzofurazan-Containing Polymers”, Macromolecular Rapid Communications, 2011, 32, 610-615.

4          J. M. Hu, S. Y. Liu* Responsive Polymers for Detection and Sensing Applications: Current Status and Future Developments”, Macromolecules, 2010, 43, 8315-8330. (Perspective Article). Highly Cited Papers by Essential Science Indicators at ISI Web of Knowledge; Most Read Articles over the last 12 months during the period of Dec 2010-Dec 2011; Ranked 6th among Top 20 Most-Cited Article in Macromolecules Journal over the Past 3 years, as of April 2012.

3              J. M. Hu, Z. S. Ge,* Y. M. Zhou, Y. F. Zhang, S. Y. Liu* Unique Thermo-Induced Sequential Gel-Sol-Gel Transition of Responsive Multiblock Copolymer-Based Hydrogels”, Macromolecules, 2010, 43, 5184–5187.

2              J. M. Hu, C. H. Li, S. Y. Liu*Hg(II)-Reactive Double Hydrophilic Block Copolymer Assemblies as Novel Multifunctional Fluorescent Probes with Improved Performance”, Langmuir, 2010, 26, 724–729.

1               J. M. Hu, D. Wang, J. Xu, Z. Y. Zhu, S. Y. Liu*Contraction and Collapsing Kinetics of Single Synthetic Polymer Chains at Small Quench Depths”, Macromolecular Chemistry and Physics, 2010, 211, 2573-2584.