Research areas
Currently, the lab has three research areas:
1, Functions of noncoding RNAs in normal and
abnormal cells. We are investigating unknown functions of classical house
keeping RNAs and novel ncRNAs. This is largely
carried out with mammalian cell cultures and pathological samples. We study
roles of these ncRNAs at the level of Biochemistry
and Cell Biology.
2, Functions of noncoding RNAs in Neural Stem
Cells (NSCs). There are many ncRNAs found in neural stem cells (including embryonic and
adult NSCs). Functions of a lot of these ncRNAs in
the proliferation and differentiation of NSCs remain unknown. We characterize
roles of these ncRNAs with cell cultures and mice
model.
3, Functions of noncoding RNAs in C. elegans. A part of my lab is studying roles of ncRNAs in the model organism, Caenorhabditis elegans. We are particularly interested in roles of
microRNAs in GABAergic D motor neurons, and roles of ncRNAs in the reactions of C. elegans to environmental factors (e.g. food).