Guan-Wu Wang

Professor of Chemistry
Organic Chemistry

Department of Chemistry
University of Science and Technology of China
Hefei, Anhui 230026, P. R. China
Tel & Fax: 86-551-3607864
Email: gwang@ustc.edu.cn

Education and Work Experince

B.S., 1983-1987, Lanzhou University
M.S., 1987-1990, Lanzhou University (with Professor You-Cheng Liu)
Ph.D., 1990-1993, Lanzhou University (with Professor You-Cheng Liu)

Postdoctoral and Research Associate:
Department of Chemistry , Fudan University , 1993-1995 (with Professor Shi-Hui Wu)
Institute for Chemical Research , Kyoto University , 1995-1996 (with Professor Koichi Komatsu)
Department of Chemistry , University of Kentucky , 1996-1997 (with Professor Mark S. Meier)
Department of Chemistry , Univeristy of Chicago , 1997-1998 (with Professor Philip E. Eaton)
Department of Chemistry , Yale University , 1999-2000 (with Professor Martin Saunders)

Professional Appointment

University of Science and Technology of China , 2000-

Associate Professor, 1995
Full Professor, 2000

Research Interests

(1) Fullerene Chemistry

We are investigating the chemistry of fullerenes (C60 and C70) both in liquid phase and in solid state. The high-speed vibration milling (HSVM) technique is used for the solvent-less reactions of fullerenes. Fullerene derivatives with cationic or anionic groups are water-soluble. Some of the water-soluble derivatives have shown intersting biological properties. They have potential application in drugs. Currently, various water-soluble fullerene derivatives are being synthesized, their physical and biological properties will be explored.

(2) Green Organic Synthesis

Organic reaction under solvent-free conditions and microwave irradiation or high-speed vibration milling is the current focus.

(3) Theoretical Calculations

Theoretical studies on the ongoing reactions in our research group are performed to better understand the reaction mechanisms.

(4) Electron Transfer Reactions

Collaborated with Professor You-Cheng Liu, electron trnasfer reactions involving coenzyme NADH models are being studied.

Selected Publications

1. Guan-Wu Wang, Koichi Komatsu,* Yasujiro Murata, and Motoo Shiro, "Synthesis and X-Ray Structure of Dumb-Bell-Shaped C₁₂₀", Nature 1997, 387, 583-586. (cover title, news reported by C & EN, news reported by Kyoto Newspaper)

2. Mark S. Meier,* Guan-Wu Wang, Robert C. Haddon, Carolyn Pratt. Brock, Michael A. Lloyd, and John P. Selegue, "Benzyne Adds Across a Closed 5-6 Ring Fusion in C₇₀: Evidence for Bond Delocalization in Fullerenes", J. Am. Chem. Soc. 1998, 120, 2337-2342.

3.Guan-Wu Wang,* Ting-Hu Zhang, Er-Hong Hao, Li-Juan Jiao, Yasujiro Murata, and Koichi Komatsu, “Solvent-Free Reactions of Fullerenes with N-Alkylglycines with and without Aldehydes under High-Speed Vibration Milling”, Tetrahedron 2003, 59, 55-60.

4. Guan-Wu Wang,* Xin-Hao Zhang, Huan Zhan, Qing-Xiang Guo, and Yun-Dong Wu, “Accurate Calculation, Prediction, and Assignment of ³He NMR Chemical Shifts of Helium-3-Encapsulated Fullerenes and Fullerene Derivatives”, J. Org. Chem. 2003, 68, 6732-6738.

5.Ting-Hu Zhang, Ping Lu, Fan Wang, and Guan-Wu Wang,* “Reaction of [60]fullerene with free radicals generated from active methylene compounds by manganese(III) acetate”, Org. Biomol. Chem. 2003, 1, 4403-4407.

6.Guan-Wu Wang, “Fullerene Mechanochemistry”, in Encyclopedia of Nanoscience and Nanotechnology, H. S. Nalwa, Ed., American Scientific Publishers: Stevenson Ranch, Vol. 3, p. 557-565, 2004. (invited book chapter).

7. Ze Zhang, Ya-Wei Dong, Guan-Wu Wang,* and Koichi Komatsu, “Highly Efficient Mechanochemical Reactions of 1, 3-Dicarbonyl Compounds with Chalcones and Azachalcones Catalyzed by Potassium Carbonate”, Synlett 2004, 61-64.

8. Yu-Jin Li, Guan-Wu Wang,* Jia-Xing Li, and You-Cheng Liu, “Cycloaddition Reactions of Hydrofullerenes with Cyano-substituted Alkenes under Basic Conditions”, New J. Chem. 2004, 28, 1042-1046.

9. Ze Zhang, Guan-Wu Wang,* Chun-Bao Miao, Ya-Wei Dong, and Ye-Bing Shen, “Solid-state Radical Reactions of 1,3-Cyclohexanediones with in situ Generated Imines Mediated by Manganese(III) Acetate under Mechanical Milling Conditions”, Chem. Commun. 2004, 1832-1833.

10. Zhong-Xiu Chen, and Guan-Wu Wang,* “One-Pot Sequential Synthesis of Acetoxylated [60]Fullerene Derivatives”, J. Org. Chem. 2005, 70, 2380-2383.

Click HERE to see a full list of publications.