Publications
2026
Nickel-Catalyzed Asymmetric Hydrophosphinamidation of Alkynes
Li Gao, Jia-Zhong Tang, Meng-Xiang Li, Jun-Ze Rong, Hoonam Tahvildari, Chang-Jiang Yang, Lin Liu, Qing-Wei Zhang*
Angew. Chem. Int. Ed., 2026, 65, e4145640.
Nickel-Catalyzed Enantioselective Synthesis of Chiral Alkenyl Sulfoxides
Li Gao, Jing-Wen Wang, Meng-Xiang Li, Ya-Qian Zhang, Lin Liu, Qing-Wei Zhang*
Org. Lett., 2026, 28, 11451–11456.
Accessing P-Chiral Diphosphines through Nickel-Catalyzed Asymmetric Hydrophosphination
Chun-Yi Xiong, Meng-Xiang Li, Wei-Han Wang, Qing-Wei Zhang*
Org. Lett., 2026, 28, 11350–11355.
Hydrogen-Bond-Directed Nickel-Catalyzed Allylation of Primary Phosphine Oxides
Wen-Qing Zhou, Yu-Xiang Zhang, Xiang Zi, Wei-Han Wang, Qing-Wei Zhang*
Precision Chemistry, 2026.
Nickel-catalyzed enantioselective synthesis of P-stereogenic azaborines
Yayu Qi, Junjie Xia, Huasu Fang, Liyan Yuwen, Jingwen Wang, Qing-Wei Zhang*
Chin. Chem. Lett., 2026, 113214.
Ni-Catalyzed Regio- and Enantioselective Synthesis of P-Chiral Dienyl Secondary Phosphine Oxides
Jin-Ming Jia, Chun-Yi Xiong, Wei-Han Wang, Qing-Wei Zhang*
Asian J. Org. Chem., 2026, 15, e70482.
Copper-Catalyzed Asymmetric Synthesis of Heteroaryl Sulfoxide
Liyan Yuwen, Yayu Qi, Tianyi Zou, Ya-Qian Zhang, Qing-Wei Zhang*
Org. Lett., 2026, 28, 5286–5291.
Diastereoselective synthesis of cyclopropyl sulfoxides via hydrosulfenation
Liyan Yuwen, Jiazhong Tang, Yayu Qi, Tianyi Zou, Shaotong Zhang, Ya-Qian Zhang, Qing-Wei Zhang*
Chem. Sci., 2026, 17, 3171–3177.
Chiral anionic ProPhenol ligand enabled nickel catalyzed enantioselective synthesis of sulfinamides
Ya-Qian Zhang, Yuxiang Zhang, Jiazhong Tang, Jiajun Wu, Jingjing Xue, Zijian Chen & Qing-Wei Zhang*
Sci. China Chem. 2026, 69, 276–282.
Chemodivergent Synthesis of β-Phosphonyl Carboxylic Acids and Acylphosphine Oxides via Ring-Opening Addition of Cyclopropenone
Siyu Zhang, Jiazhong Tang, Zhuo Huang, Shaotong Zhang, Qing-Wei Zhang*
Precision Chemistry, 2026, 4, 262–268.
2025
Regiodivergent hydrophosphination of Bicyclo[1.1.0]-Butanes under catalyst control
Zhuo Huang, Huiwen Tan, Ranran Cui, Yudong Hu, Siyu Zhang, Jinming Jia, Xinglong Zhang & Qing-Wei Zhang*
Nat. Commun., 2025, 16, 6216.
Nickel-Catalyzed Nucleophilic Substitution of Cyclopropenes by Secondary Phosphines
Huasu Fang, Liyan Yuwen, Yayu Qi, Jingwen Wang, Qing-Wei Zhang*
Synlett 2025, 36, 1780–1784.
Nickel-Catalyzed Asymmetric Synthesis of Ambiphilic Secondary Phosphine Oxides
Wei-Han Wang, Si-Yu Zhang, Yu-Xiang Zhang, Yin-Qi Wang, and Qing-Wei Zhang*
J. Am. Chem. Soc., 2025, 147, 14797–14805.
Ni(II)-catalyzed nucleophilic substitution for the synthesis of allenylselenide
Ling-Hong Zeng, Ranran Cui, Zhuo Huang and Qing-Wei Zhang*.
Chem. Commun. 2025, 61, 1192–1195.
2024
N-Heterocyclic Carbene Enabled Copper Catalyzed Asymmetric Synthesis of Pyrimidinyl Phosphine with both Axial and P-Stereogenicity
Ranran Cui, Yuxiang Zhang, Zhuo Huang, Liyan Yuwen, Yuming Xu, Qing-Wei Zhang*.
Angew. Chem. Int. Ed. 2024, 63, e202412064.
An unconventional associated outersphere mechanism for chiral sulfoxide synthesis
Li Gao, Yin-Qi Wang, Ya-Qian Zhang, Yi-Yu Liu, Qing-Wei Zhang
Trends in Chemistry 2024, 6, 406–407.
Oxidation State-Based Selectivity Tuning in Transition Metal Catalysis
Tian-Yi Zou, Qing-Wei Zhang
ChemCatChem 2024, 16, e202301423.
Capturing the Precise Structure of Liquids: The Crystalline Sponge Method for an Undergraduate Laboratory Course
Junxi Zou, Xiaoyu Wang, Xuan Liu, Yuan Zheng*, Wei Shao*, Qing-Wei Zhang*, Pingping Zhu*, Lingling Li*.
J. Chem. Educ. 2024, 101, 136–144.
Advances in Mechanistic Studies of Metal-Catalyzed Hydrophosphinylation of Non-Activated Alkynes
Yi-Yu Liu, Yudong Hu, Qing-Wei Zhang*
Chinese Journal of Organic Chemistry 2024, 44(12), 3678–3685.
Nickel-Catalyzed Enantioselective Synthesis of Dienyl Sulfoxide
Li Gao, Yinqi Wang, Ya-Qian Zhang, Yi-Han Fu, Yi-Yu Liu, Qing-Wei Zhang*.
Angew. Chem. Int. Ed. 2024, 63, e202317626.
2023
Nickel-Catalyzed Asymmetric Arylation of H-Phosphinates
Qing Zhang, Ran-ran Cui, Qing-Wei Zhang*
Synlett 2023, 34, 1819–1823.
Ni-Catalyzed Asymmetric C–P Cross-Coupling Reaction for the Synthesis of Chiral Heterocyclic Phosphine Oxides
Ranran Cui, Yinqi Wang, Liyan Yuwen, Li Gao, Zhuo Huang, Wei-Han Wang, Qing-Wei Zhang*
Org. Lett. 2023, 25, 6139–6142.
Pd-Catalysed Diastereoselective Synthesis of aza-Spirocyclic P-Stereogenic Phosphine Oxides
Bin Zhang, Xiao-Ming Zhang, Qing-Wei Zhang*
Eur. J. Org. Chem. 2023, 26, e202300265.
Nickel-catalysed enantioselective hydrosulfenation of alkynes
Ya-Qian Zhang, Lingfei Hu, Liyan Yuwen, Gang Lu*, Qing-Wei Zhang*
Nat. Catal. 2023, 6, 487–494.
NiII-Catalyzed Enantioselective Anti-Markovnikov Hydrophosphination of Unactivated Alkynes
Wei-Han Wang, Yue Wu, Peng-Jia Qi, Qing-Wei Zhang*
ACS Catal. 2023, 13, 6994–7001.
Synthesis of Cyclic 1,2-Bisphosphines by Tandem Michael Addition of 2,3-Bis(diarylphosphinyl)-1,3-butadiene
Zhenqiang Chen, Yingying Sun, Shoufeng Wang*, Qing-Wei Zhang*
Eur. J. Org. Chem. 2023, 26, e202201257.
Nickel-catalysed enantioselective reaction of secondary phosphine oxides and activated vinylcyclopropanes
Zhuo Huang, Xu-Teng Liu, Ran-ran Cui, Qing-Wei Zhang*
Org. Biomol. Chem. 2023, 21, 3096.
A Ni-catalyzed asymmetric C(sp)–P cross-coupling reaction for the synthesis of P-stereogenic alkynylphosphines
Bin Zhang, Wen-Qing Zhou, Xu-Teng Liu, Ying-ying Sun, Qing-Wei Zhang*
Chem. Sci. 2023, 14, 1286–1290.
2022
Rhodium catalyzed asymmetric synthesis of Chiraphos derivatives
Ying-Ying Sun, Bin Zhang, Liangbin Yu, Ran-ran Cui, Qingyang Zhao* and Qing-Wei Zhang*
Chinese Chemical Letters. 2022, 33, 5084.
Enantioselective synthesis of P-stereogenic allenylphosphines through Ni-catalysed propargylic substitution
Wei-Han Wang, Yue Wu, Hai-Tao Wang, Peng-Jia Qi, Wen-Ning Lan, Qing-Wei Zhang*
Nat. Synth. 2022, 1, 738.
Nickel-Catalyzed Asymmetric Synthesis of P-Stereogenic Vinyl Phosphines
Xu-Teng Liu, Yue Wu, and Qing-Wei Zhang*
Synlett 2022, 33, 301.
Ni-Catalyzed Enantioselective Benzylation of Secondary Phosphine Oxide
Wen-Qiang Cai, Qi Wei, and Qing-Wei Zhang*
Org. Lett. 2022, 24, 1258.
Ni-catalyzed asymmetric hydrophosphinylation of conjugated enynes and mechanistic studies
Ya-Qian Zhang, Xue-Yu Han, Yue Wu, Peng-Jia Qi, Qing Zhang and Qing-Wei Zhang*
Chem. Sci. 2022, 13, 4095.
2021
Ni-Catalyzed Enantioselective Allylic Alkylation of H-Phosphinates
Qing Zhang, Xu-Teng Liu, Yue Wu, and Qing-Wei Zhang*
Org. Lett. 2021, 23, 8683.
Ni-Catalyzed Asymmetric Hydrophosphination of Unactivated Alkynes
Xu-Teng Liu, Xue-Yu Han, Yue Wu, Ying-Ying Sun, Li Gao, Zhuo Huang and Qing-Wei Zhang*
J. Am. Chem. Soc. 2021, 143, 11309.
2019
Ni-Catalyzed Asymmetric Allylation of Secondary Phosphine Oxides
Xu-Teng Liu, Ya-Qian Zhang, Xue-Yu Han, Shi-Ping Sun and Qing-Wei Zhang*
J. Am. Chem. Soc. 2019, 141, 16584–16589.
Collaborative Publications
Divergent Total Synthesis of Pleurotinoid Natural Products
Jin-Bao Qiao, Jia-Yi Pei, Yuxiang Zhang, Qing-Wei Zhang* and Yu-Ming Zhao*
J. Am. Chem. Soc. 2025, 147, 40093–40098.
Rhodium hydride enabled enantioselective intermolecular C–H silylation to access acyclic stereogenic Si–H
Kun An, Wenpeng Ma, Li-Chuan Liu, Tao He, Guiyu Guan, Qing-Wei Zhang* and Wei He*
Nat. Commun. 2022, 13, 847.
Simultaneous oxidative and reductive reactions in one system by atomic design
Yafei Zhao, Huang Zhou, Xiaorong Zhu, Yunteng Qu, Can Xiong, Zhenggang Xue, Qingwei Zhang, Xiaokang Liu, Fangyao Zhou, Xiaoming Mou, Wenyu Wang, Min Chen, Ya Xiong, Xingen Lin, Yue Lin, Wenxing Chen, Hui-Juan Wang, Zheng Jiang, Lirong Zheng, Tao Yao, Juncai Dong, Shiqiang Wei, Weixin Huang, Lin Gu, Jun Luo, Yafei Li, Yuen Wu
Nat. Catal. 2021, 4, 134–143
Two-Step Carbothermal Welding To Access Atomically Dispersed Pd1 on Three-Dimensional Zirconia Nanonet for Direct Indole Synthesis
Yafei Zhao, Huang Zhou, Wenxing Chen, Yujing Tong, Chao Zhao, Yue Lin, Zheng Jiang, Qingwei Zhang, Zhenggang Xue, Weng-Chon Cheong, Benjin Jin, Fangyao Zhou, Wenyu Wang, Min Chen, Xun Hong, Juncai Dong, Shiqiang Wei, Yadong Li, Yuen Wu*
J. Am. Chem. Soc. 2019, 141, 10590
Copper-Catalyzed Trifunctionalization of Alkynes: Rapid Formation of Oxindoles Bearing Geminal Diboronates
Tao He, Bin Li, Li-Chuan Liu, Jing Wang, Wen-Peng Ma, Guang-Yu Li, Qing-Wei Zhang* and Wei He*
Chem. Eur. J. 2019, 25, 966–970
Rhodium-Catalyzed Intermolecular trans-Disilylation of Alkynones with Unactivated Disilanes
Tao He, Li-Chuan Liu, Le Guo, Bin Li, Qing-Wei Zhang* and Wei He*
Angew. Chem. Int. Ed. 2018, 57, 10868
Publications Prior to USTC
Synthesis of heteroaromatic trifluoromethyl ethers with trifluoromethyl triflate as the source of the trifluoromethoxy group
Zhang Qing-Wei, Hartwig John F.
Chem. Commun. 2018, 54, 10124.
Construction of Chiral Tetraorganosilicons by Tandem Desymmetrization of Silacyclobutanes/Intermolecular Dehydrogenative Silylation
Zhang Qing-Wei, An Kun, Liu Li Chuan, Zhang Qi, Guo Huifang, He Wei
Angew. Chem. Int. Ed. 2017, 56, 1125–1129.
Fluorodecarboxylation for the Synthesis of Trifluoromethyl Aryl Ethers
Zhang Qing-Wei, Brusoe Andrew T., Mascitti V., Hesp Kevin D., Blakemore David C., Kohrt Jeffrey T., Hartwig John F.
Angew. Chem. Int. Ed. 2016, 55, 9758.
Rhodium-Catalyzed Intramolecular C−H Silylation by Silacyclobutanes
Zhang Qing-Wei, An Kun, Liu Li Chuan, Guo Shuangxi, Jiang Chenran, Guo Huifang, He Wei
Angew. Chem. Int. Ed. 2016, 55, 6319.
Rhodium-Catalyzed Enantioselective Intramolecular C–H Silylation for the Syntheses of Planar-Chiral Metallocene Siloles
Zhang Qing-Wei, An Kun, Liu Li Chuan, Yue Yuan, He Wei
Angew. Chem. Int. Ed. 2015, 54, 6918.
Catalytic Synthesis of π-Conjugated Silole through Si–C (sp3) Bond Activation
Zhang Qing-Wei, An Kun, He Wei
Synlett 2015, 26, 1145.
Rhodium-Catalyzed Tandem Cyclization/Si–C Activation Reaction for the Synthesis of Siloles
Zhang Qing-Wei, An Kun, He Wei
Angew. Chem. Int. Ed. 2014, 53, 5667.
Catalytic intermolecular carbon electrophile induced semipinacol rearrangement
Zhang Qing-Wei, Zhang Xiao Bo, Li Bao Sheng, Xiang Kai, Zhang Fu Min, Wang Shao Hua, Tu Yong Qiang
Chem. Commun. 2013, 49, 1648.
Formal Synthesis of (−)-Cephalotaxine Based on a Tandem Hydroamination/Semipinacol Rearrangement Reaction
Zhang Qing-Wei, Xiang Kai, Tu Yong Qiang, Zhang Shu Yu, Zhang Xiao Ming, Zhao Yu Ming, Zhang Tian Cai
Chem. Asian J. 2012, 7, 894.
Brønsted Acid Catalyzed Enantioselective Semipinacol Rearrangement for the Synthesis of Chiral Spiroethers
Zhang Qing-Wei, Fan Chun An, Zhang Hai Jun, Tu Yong Qiang, Zhao Yu Ming, Gu Peiming, Chen Zhi Min
Angew. Chem. Int. Ed. 2009, 48, 8572.