Zachary J. Smith (储扎克) & Kaiqin Chu (储开芹)

Lab for Multimodal Biomedical Imaging & Therapy (MBIT),
USTC, Department of Precision Machinery and Precision Instrumentation

Up-to-date lists always available by Google Scholar: Zach & Kaiqin

(last update 02/04/2022, # denotes first author, * denotes corresponding author)


  1. R Shi#, Y Sun, J Fang, X Chen, ZJ Smith*, K Chu*, Asymmetrical illumination enables lipid droplets segmentation in Caenorhabditis elegans using epi-illumination dark field microscopy, Frontiers in Physics, in press, 2022. (link)
  2. Y Dai#, Y Yu#, X Wang, Z Jiang, K Chu, ZJ Smith*, Recent Progress in Label-Free Techniques for Characterization of Extracellular Vesicle Heteorgeneity, 中国科学:化学, in press, 2022. (link, in Chinese)
  3. Y Ma#, T Dai, Y Lei, J Zheng, M Liu, B Sui, ZJ Smith, K Chu*, L Kong*, G Peng*, Label-Free Imaging of Intracellular Organelle Dynamics Using Flat-Fielding Quantitative Phase Contrast Microscopy (FF-QPCM), Optics Express, 30(6), 9505-9520, 2022. (link)
  4. Y Pan#, S Guo, ZJ Smith*, K Chu*, Simultaneous 3D deconvolution and halo removal for spatial light interference microscopy through a two-edge apodized Wiener filter, JOSA A, 39(2), 287-296, 2022. (link)
  5. R Shi#, X Chen, J Hou, S Guo, ZJ Smith*, K Chu*, Epi-illumination dark field microscopy enables direct visualization of unlabeled small organisms with high spatial and temporal resolution, Journal of Biophotonics, 15(1), e202100185, 2022. (link)

  6. 2021

  7. Y Tang#*, X Chen, S Zhang, ZJ Smith, T Gao*, Vibrational Fingerprint Analysis of an Azo-based Resonance Raman Scattering Probe for Imaging Proton Distribution in Cellular Lysosomes, Analytical Chemistry, 93(47), 15659-15666, 2021. (link)
  8. Q Lu#, K Chu, H Dou*, ZJ Smith*, A sample-preparation-free, automated, sample-to-answer system for cell counting in human body fluids, Analytical Bioanalytical Chemistry, 413, 5025-5035, 2021. (link)
  9. S Guo#, Y Ma, Y Pan, ZJ Smith*, K Chu*, Organelle-specific phase contrast microscopy enables gentle monitoring and analysis of mitochondrial network dynamics, Biomedical Optics Express, 12(7), 4363-4379, 2021. (link)
  10. Y Tang#*, Y Zhuang, S Zhang, ZJ Smith, Y Li, X Mu, M Li, C He, X Zheng, F Pan, T Gao*, and L Zhang, Azo-Enhanced Raman Scattering for Enhancing the Sensitivity and Tuning the Frequency of Molecular Vibrations, ACS Central Science, 7(5), 768-780, 2021. (link)
  11. C Hu#, X Wang, L Liu, C Fu, K Chu, ZJ Smith*, Fast Confocal Raman Imaging via Context-Aware Compressive Sensing, Analyst, 146, 2348-2357, 2021. (link)
  12. P Gao*#, Y Ma, K Wen, M Liu, J Zheng, K Chu, ZJ Smith, L Liu, Recent Advances in Structured Illumination Microscopy, J Phys Photonics, 3, 024009, 2021. (link)

  13. 2020

  14. X Chen#, P Luo, C Hu, S Yan, D Lu, Y Li, K Chu, ZJ Smith*, Nanometer precise red blood cell sizing using a cost-effective quantitative dark field imaging system, Biomedical Optics Express, 11(10), 5950-5966, 2020. (link)
  15. X Wang#, C Hu#, K Chu, ZJ Smith*, Low Resolution Raman: The impact of spectral resolution on limit of detection and imaging speed in hyperspectral imaging, Analyst, 145, 6607, 2020. (link)
  16. Q Meng#, T Xu, ZJ Smith, K Chu*, Optical volumetric projection with large NA objectives for fast high-resolution 3D imaging of neural signals, Biomedical Optics Express, 11(7), 3769-3782 (2020). (link)
  17. Y Pan#, T Ma, Q Meng, Y Mao, K Chu, Y Men, T Pan, B Li*, J Chu, Droplet digital PCR enabled by microfluidic impact printing for absolute gene quantification, Talanta, 92(7), 5585-5594, 2020. (link)
  18. Y Dai#, S Bai#, C Hu, K Chu, B Shen*, ZJ Smith*, Combined morpho-chemical profiling of individual extracellular vesicles and functional nanoparticles without labels, Analytical Chemistry, 92(7), 5585-5594, 2020. (link, 一区,Top期刊)
  19. Z Lao#, Y Zheng, Y Dai, Y Hu*, J Ni, S Ji, Z Cai, ZJ Smith, J Li, L Zhang, D Wu*, J Chu, Nanogap Plasmonic Structures Fabricated by Switchable Capillary‐Force Driven Self‐Assembly for Localized Sensing of Anticancer Medicines with Microfluidic SERS, Advanced Functional Materials, 30(15), 1909467, 2020. (link, 一区,Top期刊)
  20. Y Li#, X Ma, W Wang, S Yan, F Liu, K Chu, G Xu, ZJ Smith*, Improving the limit of detection in portable luminescent assay readers through smart optical design, Journal of Biophotonics 13(1), e201900241, 2020. (link)

  21. 2019

  22. S Wachsmann-Hogiu#*, ZJ Smith, M Kahraman, Editorial: Plasmonic Technologies for Bioanalytical Applications, Frontiers in Chemistry, 7, 865, 2019. (link)
  23. Y Zhang#, C Li, C Hu, Q Qu, Y Cai, S Xing, H Lu, L Wang, D Huang, L Sun, T Li, X He, X Zhong, J Wang, P Gao, ZJ Smith, W Jia*, H Zhang*, Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP‐1, EMBO Reports, 20(10), e48115, 2019. (link, 一区,Top期刊)
  24. S Kheireddine#, ZJ Smith, D Nicolau, S Wachsmann-Hogiu*, Simple adaptive mobile phone screen illumination for dual phone differential phase contrast (DPDPC) microscopy , Biomedical Optics Express, 10(9), 4369-4380, 2019. (link, Editor's Pick)
  25. Y Ma#, S Guo#, Y Pan,, R Fan, ZJ Smith, S Lane, K Chu*, Quantitative Phase Microscopy with Enhanced Contrast and Improved Resolution through Ultra‐Oblique Illumination (UO‐QPM), Journal of Biophotonics, 12(10), e201900011, 2019. (link)
  26. Y Li#, R Zheng#, Y Wu, K Chu, Q Xu*, M Sun*, ZJ Smith*, A low‐cost, automated parasite diagnostic system via a portable, robotic microscope and deep learning, Journal of Biophotonics, 12(9), e201800410, 2019. (link)
  27. C Xiao#, ZJ Smith, K Chu*, Simultaneous recovery of both bright and dim structures from noisy fluorescence microscopy images using a modified TV constraint, Journal of Microscopy, 275(11), 24-35, 2019. (link)
  28. Li X#, Deng Q#, Liu H, Lei Y, Fan P, Wang B, Chen Y, ZJ Smith, Tang Y*, Gao T*, A smart preparation strategy for point-of-care cellular counting of trace volumes of human blood, Anal Bioanal Chem, 411(13), 2767-2780, 2019. (link, Paper in Forefront)
  29. G Liu#, F Dong#, C Fu*, ZJ Smith*, Automated morphometry toolbox for analysis of microscopic model organisms using simple bright-field imaging, Biology Open, 8, bio.037788, 2019. (link)
  30. S Kheireddine#, AS Perumal, ZJ Smith, DV Nicolau, S Wachsmann-Hogiu*, Dual-phone illumination-imaging system for high resolution and large field of view multi-modal microscopy, Lab on a Chip, 19, 825-836, 2019. (link), (一区,Top期刊)

  31. 2018

  32. L Tong#, J Kauer, X Chen, K Chu, H Dou*, ZJ Smith*, Screening of nutritional and genetic anemias using elastic light scattering, Lab on a Chip, 18, 3263-3271, 2018. (link), (一区,Top期刊, Cover article
  33. S Van Cleuvenbergen#*, ZJ Smith, O Deschaume, C Bartic, S Wachsmann-Hogiu, T Verbiest, MA van der Veen*, Morphology and structure of ZIF-8 during crystallisation measured by dynamic angle-resolved second harmonic scattering, Nature Communications, 9, 3418, 2018. (link), (一区,Top期刊)
  34. Q Lu#, G Liu, C Xiao, C Hu, S Zhang, RX Xu, K Chu, Q Xu*, ZJ Smith*, A modular, open-source, slide-scanning microscope for diagnostic applications in resource-constrained settings, PLOS ONE, 13(3), e0194063, 2018. (link)
  35. J Ye#, G Liu#, P Liu, S Zhang, P Shao, ZJ Smith, C Liu, RX Xu*, Benchtop and animal validation of a portable fluorescence microscopic imaging system for potential use in cholecystectomy, Journal of Biomedical Optics, 23(2), 020504, 2018. (link)
  36. B Cai, X Zhai, Z Wang, Y Shen, RX Xu, ZJ Smith, Q Wen*, K Chu*, Optical volumetric projection for fast 3D imaging through circularly symmetric pupil engineering, Biomedical Optics Express, 9 (2), 437-446, 2018. (link)
  37. Y Ma, D Li, ZJ Smith, D Li*, K Chu*, Structured illumination microscopy with inter‐leaved reconstruction (SIMILR), Journal of Biophotonics, 11(2), e201700090, 2018. (link)
  38. D Xie, Y Xie, P Liu, L Tong, C Hu, P Shao, K Chu*, ZJ Smith*, Performance of a cost‐effective and automated blood counting system for resource‐limited settings operated by trained and untrained users, Journal of Biophotonics, 11(2), e201700030, 2018. (link)

  39. 2017

  40. L Tong, J Kauer, S Wachsmann-Hogiu, K Chu, H Dou*, ZJ Smith*, A new red cell index and portable RBC analyzer for screening of iron deficiency and Thalassemia minor in a Chinese population, Scientific Reports, 7, 10510, 2017. (link)
  41. R Ferraz de Menezes, CM Harvey, ME Márquez de Martínez Gerbi, ZJ Smith, D Smith, JC Ivaldi, A Phillips, JW Chan, S Wachsmann‐Hogiu, Fs‐laser ablation of teeth is temperature limited and provides information about the ablated components, Journal of Biophotonics, 10(10), 1292-1304, 2017
  42. S Jiang, X Zhang, Y Zhang, C Hu, R Zhang, Y Zhang, Y Liao, ZJ Smith*, Z Dong*, JG Hou, Subnanometer-resolved chemical imaging via multivariate analysis of tip-enhanced Raman maps, Light: Science & Applications, 6, e17098, 2017 (link) (一区,Top期刊)
  43. RP Carney, S Hazari, M Colquhoun, D Tran, B Hwang, MS Mulligan, JD Bryers, E Girda, GS Leiserowitz, ZJ Smith, and KS Lam, Multispectral Optical Tweezers for Biochemical Fingerprinting of CD9-Positive Exosome Subpopulations, Analytical Chemistry, 89(10), 5357–5363, 2017 (一区,Top期刊)
  44. NK Das, Y Dai, P Liu, C Hu, L Tong, X Chen, ZJ Smith*, Raman Plus X: Biomedical Applications of Multimodal Raman Spectroscopy, Sensors 17(7), 1592, 2017
  45. EI Buzás#*, C Gardiner#*, C Lee#*, ZJ Smith#*, Single particle analysis: Methods for detection of platelet extracellular vesicles in suspension (excluding flow cytometry), Platelets 28(3), 249-255, 2017

  46. 2016

  47. ZJ Smith#*, C Lee, T Rojalin, S Wachsmann-Hogiu, Comment on “Label-Free Single Exosome Detection Using Frequency Locked Microtoroid Optical Resonators", ACS Photonics, 3(4), 716-717, 2016, (一区,Top期刊)
  48. RK Gill#, ZJ Smith, C Lee, S Wachsmann‐Hogiu, The effects of laser repetition rate on femtosecond laser ablation of dry bone: a thermal and LIBS study, Journal of Biophotonics, 9(1-2), 171-180, 2016

  49. 2015

  50. ZJ Smith#, C Lee, T Rojalin, RP Carney, S Hazari, A Knudson, K Lam, H Saari, E Lazaro Ibañez, T Viitala, T Laaksonen, M Yliperttula, S Wachsmann-Hogiu, Single exosome study reveals subpopulations distributed among cell lines with variability related to membrane content, Journal of Extracellular Vesicles, 4(1), 28533, 2015
  51. RK Gill#, ZJ Smith#, RR Panchal, JW Bishop, R Gandour-Edwards, S Wachsmann-Hogiu, Preliminary fsLIBS study on bone tumors, Biomedical Optics Express, 6(12), 4850-4858, 2015

Papers prior to joining MBIT: see Google Scholar (links above)