Publications
2020
1. Gao L*, Chang S*, Xia W, Wang X, Zhang C, Cheng L, Liu X, Chen L, Shi Q, Huang J, Xu EJ#, Shan G#. Circular RNAs from BOULE play conserved roles in protection against stress induced fertility decline. Science Advances. 2020; 6: eabb7426. [PDF, Supp.]
2. Chen H, Shan G#. The physiological function of long-noncoding RNAs. Noncoding RNA Research. 2020; 5(4): 178–184. [PDF]
3. Yin Y, Lu JY, Zhang X, Shao W, Xu Y, Li P, Hong Y, Cui L, Shan G, Tian B, Zhang QC, Shen X#. U1 snRNP regulates chromatin retention of noncoding RNAs. Nature. 2020; 580(7801):147-150. [PubMed]
4. Liu X, Wang X, Li J, Hu S, Deng Y, Yin H, Bao X, Zhang QC, Wang G, Wang B, Shi Q, Shan G#. Identification of mecciRNAs and their roles in the mitochondrial entry of proteins. Sci China Life Sci. 2020; 63(10):1429-1449. [PDF, Supp., Supp1.]
5. Zhou Y, Liu H, Wang J, Wang X, Qian L, Xu F, Song W, Wu D, Shen Z, Feng D, Ling B, Xiao W, Shan G, Chen L#. ΔNp63α exerts antitumor functions in cervical squamous cell carcinoma. Oncogene. 2020; 39(4):905-921. [PDF]
2019
1. Wei S, Chen H, Dzakah EE, Yu B, Wang X, Fu T, Li J, Liu L, Fang S, Liu W, Shan G#. Systematic evaluation of C. elegans lincRNAs with CRISPR knockout mutants. Genome Biol. 2019; 8;20(1):7. [PDF]
2. Wang C, Yang Y, Zhang G, Li J, Wu X, Ma X, Shan G, Mei Y#. Long noncoding RNA EMS connects c-Myc to cell cycle control and tumorigenesis. Proc Natl Acad Sci U S A. 2019; 116(29):14620-14629. [PubMed]
3. Jia R, Xiao MS, Li Z, Shan G, Huang C#. Defining an evolutionarily conserved role of GW182 in circular RNA degradation. Cell Discov. 2019; 5:45. [PubMed]
4. Sheng Z, Wang X, Xu G, Shan G, Chen L#. Analyses of a Panel of Transcripts Identified From a Small Sample Size and Construction of RNA Networks in Hepatocellular Carcinoma. Front Genet. 2019; 10:431. [PDF]
5. Song W, Wang J, Liu H, Zhu C, Xu F, Qian L, Shen Z, Zhu J, Yin S, Qin J, Chen L, Wu D, Nashan B, Shan G, Xiao W, Zhou Y#. Effects of LncRNA Lnc-LIF-AS on cell proliferation, migration and invasion in a human cervical cancer cell line. Cytokine. 2019; 120:165-175. [PubMed]
6. Wu M, Liu Y, Zhang H, Lian M, Chen J, Jiang H, Xu Y, Shan G, Wu S#. Intravenous injection of l-aspartic acid β-hydroxamate attenuates choroidal neovascularization via anti-VEGF and anti-inflammation. Exp Eye Res. 2019; 182:93-100. [PubMed]
2018
1. Dzakah EE, Waqas A, Wei S, Yu B, Wang X, Fu T, Liu L, Shan G#. Loss of miR-83 extends lifespan and affects target gene expression in an age-dependent manner in Caenorhabditis elegans. J Genet Genomics. 2018; 45(12):651-662. [PDF]
2. Wang X, Shan G#. Nonradioactive Northern Blot of circRNAs. Methods Mol Biol. 2018; 1724:135-141. [PDF]
3. Chen L, Dzakah EE, Shan G#. Targetable long non-coding RNAs in cancer treatments. Cancer Lett. 2018; 418:119-124. [PDF]
4. Awan HM*, Shah A*, Rashid F*, Wei S, Chen L, Shan G#. Comparing two approaches of miR-34a target identification, biotinylated-miRNA pulldown vs miRNA overexpression. RNA Biol. 2018; 15(1):55-61. [PDF]
5. Yang L, Shang Z, Long S, Wang N, Shan G, Zhang R#. Roles of genetic and microenvironmental factors in cancer epithelial-to-mesenchymal transition and therapeutic implication. Exp Cell Res. 2018; 370(2):190-197. [PubMed]
2017
1. Yu B, Wang X, Wei S, Fu T, Dzakah EE, Waqas A, Walthall WW, Shan G#. Convergent Transcriptional Programs Regulate cAMP Levels in C. elegans GABAergic Motor Neurons. Dev Cell. 2017; 43(2):212-226.e7. [PDF, Supp.]
2. Shah A*, Rashid F*, Awan HM*, Hu S, Wang X, Chen L, Shan G#. The DEAD-Box RNA Helicase DDX3 Interacts with m6A RNA Demethylase ALKBH5. Stem Cells Int. 2017; 2017:8596135. [PDF]
3. Rashid F*, Awan HM*, Shah A*, Chen L, Shan G#. Induction of miR-3648 Upon ER Stress and Its Regulatory Role in Cell Proliferation. Int J Mol Sci. 2017; 18(7). pii: E1375. [PDF]
4. Awan HM*, Shah A*, Rashid F*, Shan G#. Primate-specific Long Non-coding RNAs and MicroRNAs. Genomics Proteomics Bioinformatics. 2017; 15(3):187-195. [PDF]
5. Qian L, Xu F, Wang X, Jiang M, Wang J, Song W, Wu D, Shen Z, Feng D, Ling B, Cheng Y, Xiao W, Shan G, Zhou Y#. LncRNA expression profile of ΔNp63α in cervical squamous cancers and its suppressive effects on LIF expression. Cytokine. 2017; 96:114-122. [PubMed]
6. Wang F, Song W, Zhao H, Ma Y, Li Y, Zhai D, Pi J, Si Y, Xu J, Dong L, Su R, Zhang M, Zhu Y, Ren X, Miao F, Liu W, Li F, Zhang J, He A, Shan G, Hui J, Wang L, Yu J#. The RNA-binding protein QKI5 regulates primary miR-124-1 processing via a distal RNA motif during erythropoiesis. Cell Res. 2017; 27(3):416-439. [PubMed]
2016
1. Hu S*, Wang X*, Shan G#. Insertion of an Alu element in an lncRNA leads to primate specific modulation of alternative splicing. Nat Struct Mol Biol. 2016; 23(11):1011-1019. [PDF, Supp.]
2. Gao X, Zhang F, Hu J, Cai W, Shan G, Dai D, Huang K, Wang G#. MicroRNAs modulate adaption to multiple abiotic stresses in Chlamydomonas reinhardtii. Sci Rep. 2016; 6:38228. [PubMed]
3. Waqas A, Shan G#. Uptake and Reaction of C. elegans to Environmental RNAs. Non-coding RNAs and Inter-kingdom Communication. Springer International Publishing, 2016; pp117-124. [PDF]
4. Rashid F, Shah A, Shan G#. Long Non-coding RNAs in the Cytoplasm. Genomics, proteomics & bioinformatics. 2016; 14(2):73-80. [PDF]
5. Yu B, Shan G#. Functions of long noncoding RNAs in the nucleus. Nucleus. 2016; 7(2):155-66. [PDF]
6. Hu S, Shan G#. LncRNAs in stem cells. Stem Cells Int. 2016; 2016:2681925. [PDF]
7. Zhou Y, Xu F, Tao F, Feng D, Ling B, Qian L, Yang X, Wang Q, Wang H, Zhao W, Cheng Y, Shan G, Kalvakolanu DV, Xiao W#. GRIM-19 Restores Cervical Cancer Cell Senescence by Repressing hTERT Transcription. J Interferon Cytokine Res. 2016; 36(8):506-15. [PubMed]
8. Li G, Wu X, Qian W, Cai H, Sun X, Zhang W, Tan S, Wu Z, Qian P, Ding K, Lu X, Zhang X, Yan H, Song H, Guang S, Wu Q, Lobie PE, Shan G, Zhu T#. CCAR1 5' UTR as a natural miRancer of miR-1254 overrides tamoxifen resistance. Cell Res. 2016; 26(6):655-73. [PubMed]
2015
2. Chen L, Huang C, Wang X, Shan Ge#. Circular RNAs in Eukaryotic Cells. Curr Genomics. 2015; 16(5):312-8. [PDF]
3. Chen L, Shan Ge#. Circular RNAs remain peculiarly unclear in biogenesis and function. Sci China Life Sci. 2015; 58(6):616-8. [PDF]
4. Huang C, Shan Ge#. What happens at or after transcription: Insights into circRNA biogenesis and function. Transcription. 2015; 6(4): 61-64. [PDF]
5. Chen L, Rashid F, Shah A, Awan HM, Wu M, Liu A, Wang J, Zhu T, Luo Z, Shan Ge#. The isolation of an RNA aptamer targeting to p53 protein with single amino acid mutation. Proc Natl Acad Sci U S A. 2015; 112(32):10002-7. [PDF, Supp.]
7. Dai L, Huang C, Chen L, Shan G, Li Z#.Altered expression of microRNAs in the response to ER stress. Science Bulletin. 2015; 60(2):202-209. [PDF]
2013-2014
1. Deng L, Shang L, Bai S, Chen J, He X, Trevino RM, Chen S, Li X, Meng X, Yu B, Wang X, Liu Y, McDermott SP, Ariazi AE, Ginestier C, Ibarra I, Ke J, Luther TK, Clouthier SG, Xu L, Shan G, Song E, Yao H, Hannon GJ, Weiss SJ, Wicha MS, Liu S#. microRNA100 inhibits self-renewal of breast cancer stem-like cells and breast tumor development. Cancer Res. 2014 Nov 15;74(22):6648-60. [Epub ahead of print] [PubMed]
2. Cai J, Yin G, Lin B, Wang X, Liu X, Chen X, Yan D, Shan G, Qu J, Wu S#. Roles of NFκB-miR-29s-MMP-2 circuitry in experimental choroidal neovascularization. J. Neuroinflammation. 2014; 11:88. doi: 10.1186/1742-2094-11-88. [PubMed]
3. Kuang XL, Liu F, Chen H, Li Y, Liu Y, Xiao J, Shan G, Li M, Snider BJ, Qu J, Barger SW, Wu S#. Reductions of the components of the calreticulin/calnexin quality-control system by proteasome inhibitors and their relevance in a rodent model of Parkinson's disease. J Neurosci Res. 2014; 92(10):1319-29. [PubMed]
4. Shan G#, Guang S. Chinese worm community made delightful wiggles in Hefei September 6 to September 8, 2013. Sci China Life Sci. 2013 Sep 27. [PDF]
5. Tian H, Cao YX, Zhang XS, Liao WP, Yi YH, Lian J, Liu L, Huang HL, Liu WJ, Yin MM, Liang M, Shan G, Sun F#. The targeting and functions of miRNA-383 are mediated by FMRP during spermatogenesis. Cell Death Dis. 2013; 4:e617. [PubMed]
6, LF Meng, L Chen, ZY Li, ZX Wu, G Shan#. Environmental RNA interference in animals. Chinese Science Bulletin, 2013; 58(35):4418-4425. [PDF]
7, Meng L, Chen L, Li Z, Wu ZX, Shan G#. Roles of MicroRNAs in the Caenorhabditis elegans Nervous System. J Genet Genomics. 2013; 40(9):445-452. [PDF]
10, Yang L, Meng Y, Bao C, Liu W, Ma C, Li A, Xuan Z, Shan G#, Jia Y#. Robustness and backbone motif of a cancer network regulated by miR-17-92 cluster during the G1/S transition. PLoS One. 2013;8(3):e57009. [PDF]2010-2012
1, Liu H*, Wang X*, Wang HD, Wu J, Ren J, Meng L, Wu Q, Dong H, Wu J, Kao TY, Ge Q, Wu ZX, Yuh CH, Shan G#. Escherichia coli noncoding RNAs can affect gene expression and physiology of Caenorhabditis elegans. Nature Communications, 2012, 25 (3): 1073. doi: 10.1038/ncomms2071.[PDF,Supp.][Highlighted in Nature Reviews Genetics][Highlighted in Nature Reviews Microbiology]
2, Hu S, Wu J, Chen L, Shan G#. Signals from noncoding RNAs: Unconventional roles for conventional pol III transcripts. The International Journal of Biochemistry & Cell Biology, 2012; 44(11): 1847-51. doi: 10.1016/j.biocel.2012.07.013. [PDF]
3, LIN Mei, WU Jing, SHAN Ge#. Noncoding RNAs: different roles in tumorigenesis. Chinese Science Bulletin, 2012; 57(9): 959-965. doi: 10.1007/s11434-011-4917-x. [PDF]
4, Gong J, Tong Y, Zhang HM, Wang K, Hu T, Shan G, Sun J, Guo AY. Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis. Human Mutation, 2012; 33(1): 254-63. doi: 10.1002/humu.21641. [PDF]
5, Luo Y*, Shan G*, Guo W*, Smrt RD, Johnson EB, Li X, Pfeiffer RL, Szulwach KE, Duan R, Barkho BZ, Li W, Liu C, Jin P, Zhao X. Fragile X Mental Retardation Protein Regulates Proliferation and Differentiation of Adult NeuralStem/ProgenitorCells. PLOS Genetics 2010, 6(4):e1000898. [PDF]
6, Ge Shan#. RNA interference as gene knockdown technique. The International Journal of Biochemistry & Cell Biology 2010, 42(8):1243-51. [PDF]
Before 2010
1, N. Shen*, J. Ko*, G. Xiao*, D. Wesolowski, G. Shan, B. Geller, M. Izadjoo, S. Altman. Inactivation of expression of several genes in a variety of bacterial species by the EGS technology. P.N.A.S., 2009,106(20): 8163-8. [PDF]
2, Shan G. and Jin P. RNA Interference to Treat Human Diseases. Volume 4 pp 241-251. In Wiley Encyclopedia of Chemical Biology. 2009, John Wiley & Sons, Hoboken. [PDF]
3, G. Shan, Y. Li, Zhang J, Li W, Szulwach KE, Duan R, Faghihi MA, Khalil AM, Lu L, Paroo Z, Chan AW, Shi Z, Liu Q, Wahlestedt C, He C, Jin P. A small molecule enhances RNA interference and promotes microRNA processing. Nature Biotechnology. 2008, 26(8):933-40. [PDF,Supp.][Recommended in Faculy of 1000]
4, G. Shan, Walthall WW. Copulation in C. elegans requires a nuclear hormone receptor. Developmental Biology. 2008, 322(1):11-20. [PDF]
5, G. Shan, S. Xu, P. Jin. FXTAS: a bad RNA and a hope for a cure. Expert Opinion on Biological Therapy. 2008, 8(3):249-53. [PDF]
6, D. C. Zarnescu, G. Shan, S. T. Warren, P. Jin. Come FLY with us: toward understanding fragile X syndrome. Genes, Brain and Behavior. 2005, 4(6):385-92. [PDF]
7, Shan G, Kim K, Li C, Walthall WW. Convergent genetic programs regulate similarities and differences between related motor neuron classes in Caenorhabditis elegans. Developmental Biology. 2005, 280(2):494-503. [PDF]
8, Xu H, Yang Z, Cui N, Giwa LR, Abdulkadir L, Patel M, Sharma P, Shan G, Shen W, Jiang C. Molecular determinants for the distinct pH sensitivity of Kir1.1 and Kir4.1 channels. Am J Physiol Cell Physiol. 2000, 279(5):C1464-71. [PDF]
9, Shan G,Gao A, Kuang Y, Yang X, Dong Q, Zhao F, Zhang M, Wang Y, Kamada M., Yan Y. Immune response and antifertility of female rats following mucosal immunization with recombinant Salmonella dublin and recombinant Vaccinia virus expressing YAL-198 fusion proteins. Reproduction & Contraception. 1999, 19(2):85-95.
*co-first authors; # corresponding author