Dr. Xiaodong Ye (叶晓东)

    Department of Chemical Physics

    University of Science and Technology of China

    96 Jinzhai Road, Hefei, Anhui 230026, China

    Phone (office): 0551-63606742

    E-mail: xdye@ustc.edu.cn

    Researcher ID: www.researcherid.com/rid/A-6983-2010

    Google Scholar: scholar.google.com/xiaodongye




9/2006-9/2007, Postdoctoral Fellowship, Department of Chemistry, The Chinese University of Hong Kong, Supervisor: Prof. Chi Wu


11/2001-1/2003, Visiting Ph.D. Student, Department of Chemistry, University of Toronto, Canada, Supervisor: Prof. Mitchell A. Winnik


9/2000-7/2006, Ph.D., Department of Chemical Physics, University of Science and Technology of China, P.R.China, Supervisor: Prof. Chi Wu


9/1996-7/2000, Bachelor, Department of Chemical Physics, University of Science and Technology of China, P.R.China





6/2014-now, Associate Professor, Department of Chemical Physics, University of Science and Technology of China, P.R.China


06/2008-09/2009, Visiting Scholar, Department of Biomedical Engineering, Duke University, Supervisor: Prof. Kam W. Leong


10/2007-6/2014, Lecturer, Department of Chemical Physics, University of Science and Technology of China, P.R.China



Research Interests


1. Design and development of advanced drug delivery systems


2. Folding kinetics of synthetic polymers and biopolymers investigated by laser-induced temperature jump and pH jump


3. Interactions between DNA and small molecules or proteins investigated by analytical ultracentrifugation (AUC)


4. Purification, characterization, and application of plant-based proteins





Teaching at USTC


1. Physical Chemistry (II) for undergraduates, 2010 - now


2. Intermolecular Forces for graduate students and undergraduates, 2011 - now


3. Applied Physical Chemistry for graduate students, 2016 - now


4. Chemical Physics Experiment for graduate students and undergraduates ("Measurement of the size and size distribution of nanoparticles by dynamic light scattering"), 2010-now



Selected Publications


35. Xiaodong Ye*, Yonggang Chen, Chi Wu*, "How is the z-Average Molar Mass Related to the Sedimentation Data?",  Macromol. Chem. Phys. 2022, 2200331.  [Full Text in PDF]


34. Kang Ni, Yating Gao, Xiaodong Ye*, "Study on the Structure and Formation Mechanism of 15S Globulin of Soybeans",  Food Hydrocolloids, 2021, 113, 106461.  [Full Text in PDF]


33. Miao Zhang, Nairong Hao, Yating Gao, Lianwei Li, Xiaodong Ye*, "Characterization of Mixed Solutions of Hyperbranched and Linear Polystyrenes by a Combination of Size-Exclusion Chromatrography and Analtyical Ultracentrifugation",  Journal of Polymer Science, 2020, 58, 756-765.  [Full Text in PDF]


32. Muhammad Waqas Ali, Siyuan Cheng, Jianhao Si, Muhammad Siddiq, Xiaodong Ye*, "Synthesis and Characterization of Degradable Hyperbranched Poly(2-ethyl-2-oxazoline)",  Journal of Polymer Science Part A: Polymer Chemistry, 2019, 57, 2030-2037.  [Full Text in PDF]


31. Jianhao Si, Nairong Hao, Miao Zhang, Siyuan Cheng, Anhong Liu, Lianwei Li*, Xiaodong Ye*, "Universal Synthetic Strategy for the Construction of Topological Polystyrenesulfonates: The Importance of Linkage Stability during Sulfonation", ACS Macro Lett. 2019, 8, 730-736.  [Full Text in PDF]


30. Jinxian Yang, Yixia Li, Nairong Hao, Ahmad Umair, Anhong Liu, Lianwei Li*, Xiaodong Ye*, "Preparation and Controlled Degradation of Model Amphiphilic Long-Subchain Hyperbranched Copolymers: Hyperblock versus Hypergraft", Macromolecules 2019, 52, 1173-1187.  [Full Text in PDF]


29. Yixia Li, Jianhao Si, Haiyan Fan, Xiaodong Ye*, "Effect of pH and Content of Reduction-Sensitive Copolymer on the Guest Exchange Kinetics of Micelles", Journal of Polymer Science Part B: Polymer Physics, 2018, 56, 1636-1644. [Full Text in PDF]


28. Yixia Li, Jianhao Si, Haiyan Fan, Jinxian Yang, Xiaodong Ye*, "Reduction-responsive Diblock Copolymer-modified Gold Nanorods for Enhanced Cellular Uptake", RSC Advances, 2018, 8, 27546-27555. [Full Text in PDF]


27. Yating Gao, Tianlei Guang, Xiaodong Ye*, "Sedimentation Velocity Analysis of TMPyP4-Induced Dimer Formation of Human Telomeric G-quadruplex", RSC Advances, 2017, 7, 55098-55105. [Full Text in PDF]


26. Haiyan Fan, Yixia Li, Jinxian Yang, Xiaodong Ye*, "Effect of Hydrophobic Chain Length on the Stability and Guest Exchange Behavior of Shell-Sheddable Micelles Formed by Disulfide-Linked Diblock Copolymers", The Journal of Physical Chemistry B, 2017, 121, 9708-9717. [Full Text in PDF]


25. Xiaodong Ye, Kejin Zhou, Chi Wu*, "One Intellectual Problem in Polymer Research - the Coil-to-Globule Conformation Transition of Flexible Chains", Acta Polymerica Sinica, 2017, 9, 1389-1399. [Full Text in PDF]


24. Jinxian Yang, Lianwei Li, Chunfeng Ma, Xiaodong Ye*, "Degradable Polyurethane with Poly(2-ethyl-2-oxazoline) Brushes for Protein Resistance", RSC Advances, 2016, 6, 69930-69938. [Full Text in PDF]


23. Yating Gao, Sha Wu, Xiaodong Ye*, "The Effects of Monovalent Metal Ions on the Conformation of Human Telomere DNA using Analytical Ultracentrifugation", Soft Matter 2016, 12, 5959-5967.  [Full Text in PDF]


22. Yating Gao, Jinxian Yang, Haiyan Fan, Yanwei Ding, Xiaodong Ye*, "Insight into the Effect of Methylated Urea on the Phase Transition of Aqueous Solutions of Poly(N-isopropylacrylamide) by Microcalorimetry: Hydrogen Bonding and van der Waals Interactions", Journal of Polymer Science Part B: Polymer Physics, 2016, 54, 1145-1151. [Full Text in PDF]


21. Xiao-Jiao Du, Ji-Long Wang, Wei-Wei Liu, Jin-Xian Yang, Chun-Yang Sun, Rong Sun, Hong-Jun li, Song Shen, Ying-Li Luo, Xiaodong Ye*, Yan-Hua Zhu, Xian-Zhu Yang, Jun Wang*, "Regulating the Surface Poly(ethylene glycol) Density of Polymeric Nanoparticles and Evaluating its Role in Drug Delivery in vivo", Biomaterials 2015, 69, 1-11.  [Full Text in PDF]


20. Xiaoyan Wang, Xiaodong Ye*, Guangzhao Zhang, "Investigation of pH-induced Conformational Change and Hydration of Poly(methacrylic acid) by Analytical Ultracentrifugation", Soft Matter 2015, 11, 5381-5388.  [Full Text in PDF]


19. Jinxian Yang, Lianwei Li*, Zongyang Jing, Xiaodong Ye*, Chi Wu, "Construction and Properties of Hyperbranched Block Copolymer with Independently Adjustable Heterosubchains", Macromolecules 2014, 47, 8437-8445.  [Full Text in PDF]


18. Yating Gao, Jinxian Yang, Yanwei Ding, Xiaodong Ye*, "Effect of Urea on Phase Transition of Poly(N-isopropylacrylamide) Investigated by Differential Scanning Calorimetry", The Journal of Physical Chemistry B, 2014, 118, 9460-9466. [Full Text in PDF]


17. Xu Wang, Lianwei Li*, Xiaodong Ye*, Chi Wu, "Comparative Study of Solution Properties of Amphiphilic 8-Shaped Cyclic-(Polystyrene-b-Poly(acrylic acid))2 and Its Linear Precursor",  Macromolecules 2014, 47, 2487-2495.  [Full Text in PDF]


16. Lianwei Li*, Xu Wang, Jinxian Yang, Xiaodong Ye*, Chi Wu, "Degradation Kinetics of Model Hyperbranched Chains with Uniform Subchains and Controlled Locations of Cleavable Disulfide Linkages",  Macromolecules 2014, 47, 650-658.  [Full Text in PDF]


15. Sha Wu, Xiaoyan Wang, Xiaodong Ye*, Guangzhao Zhang*, "pH-induced Conformation Change and Dimerization of DNA Chains Investigated by Analytical Ultracentrifugation", The Journal of Physical Chemistry B, 2013, 117, 11541-11547. [Full Text in PDF]


14. Xiaodong Ye*, Jinxian Yang, Jaweria Ambreen, "Scaling Laws Between the Hydrodynamic Parameters and Molecular Weight of Linear Poly(2-ethyl-2-oxazoline)", RSC Advances, 2013, 3, 15108-15113. [Full Text in PDF]


13. Yijie Lu, Xiaodong Ye*, Kejin Zhou, Wenjing Shi, "A Comparative Study of Urea-Induced Aggregation of Collapsed Poly(N-isopropylacryalmide) and Poly(N,N-diethylacrylamide) Chains in Aqueous Solutions", The Journal of Physical Chemistry B, 2013, 117, 7481-7488. [Full Text in PDF]


12. Jaweria Ambreen, Jinxian Yang, Xiaodong Ye*, Mohammad Siddiq, "Effect of Carbon Chain Length of Monocarboxylic acids on Cloud Point Temperature of Poly(2-ethyl-2-oxazoline)", Colloid and Polymer Science, 2013, 291, 919-925. [Full Text in PDF]


11. Long-Fei Wang, Ling-Ling Wang, Xiaodong Ye*, Wen-Wei Li, Xue-Mei Ren, Guo-Ping Sheng, Han-Qing Yu*, and Xiang-Ke Wang, "Coagulation Kinetics of Humic Aggregates in Mono- and Di-Valent Electrolyte Solutions",  Enviromental Science & Technology, 2013, 47, 5042-5049. [Full Text in PDF]


10. Ling-Ling Wang, Long-Fei Wang, Xue-Mei Ren, Xiaodong Ye*, Wen-Wei Li, Shi-Jie Yuan, Min Sun, Guo-Ping Sheng, Han-Qing Yu*, and Xiang-Ke Wang, "pH Dependence of Structure and Surface Properties of Microbial EPS",  Enviromental Science & Technology, 2012, 46, 737-744. [Full Text in PDF]


9. Yijie Lu, Xiaodong Ye*, Junfang Li, Chunliang Li, Shilin Liu, "Kinetics of Laser-Heating-Induced Phase Transition of Poly(N-isopropylacrylamide) Chains in Dilute and Semidilute Solutions", The Journal of Physical Chemistry B, 2011, 115, 12001-12006. [Full Text in PDF]


8. Xiaodong Ye, Diane Fels, Artak Tovmasyan, Katherine M. Aird, Casey Dedeugd, Jennifer L. Allenswarth, Ivan Kos, Won Park, Ivan Spasojevic, Gayathri R. Devi, Mark W. Dewhirst, Kam W. Leong, Ines Batinic-Haberle*, "Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate", Free Radical Research, 2011, 45, 1289-1306. [Full Text in PDF]


7. Xiaodong Ye*, Yanwei Ding, Junfang Li, "Scaling of the Molecular Weight-Dependent Thermal Volume Transition of Poly(N-isopropylacrylamide)", Journal of Polymer Science Part B: Polymer Physics, 2010, 48, 1388-1393. [Full Text in PDF]


6. Xiaodong Ye*, Jingyi Fei, Kui Xu, Ruke Bai, "Effect of Polystyrene-b-poly(ethylene oxide) on Self-Assembly of Polystyrene-b-poly(N-isopropylacrylamide) in Aqueous Solution", Journal of Polymer Science Part B: Polymer Physics, 2010, 48, 1168-1174. [Full Text in PDF]


5. Xiaodong Ye*, Jingyi Fei, Juan Guan, Xuechang Zhou, Guangzhao Zhang, "Dispersion of Polystyrene Inside Polystyrene-b-poly(N-isopropylacrylamide) Micelles in Water", Journal of Polymer Science Part B: Polymer Physics, 2010, 48, 749-755. [Full Text in PDF]


4. Xiaodong Ye, Yijie Lu, Shilin Liu*, Guangzhao Zhang, Chi Wu*, "Ultrafast Infrared Heating Laser Pulse-Induced Micellization Kinetics of Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide) in Water",  Langmuir 2007, 23, 10366-10371. [Full Text in PDF]


3. Xiaodong Ye, Yijie Lu, Lei Shen, Yanwei Ding, Shilin Liu, Guangzhao Zhang, Chi Wu*, "How Many Stages in the Coil-to-Globule Transition of Linear Homopolymer Chains in a Dilute Solutions?",  Macromolecules 2007, 40, 4750-4752. [Full Text in PDF]


2. Xiaodong Ye, Jun Wu, Jung Kwon Oh, Mitchell A. Winnik*, and Chi Wu, "Effect of Pluronic Surfactants on the Polymer Diffusion Rate in Poly(butyl methacrylate) Latex Films", Macromolecules, 2003, 36, 8886-8889. [Full Text in PDF]


1. Xiaodong Ye, Jos Paulo Farinha, Jung Kwon Oh, Mitchell A.Winnik*, and Chi Wu, "Polymer Diffusion PBMA Latex Films Using A Polymerizable Benzophenone Derivative As An Energy Transfer Acceptor", Macromolecules, 2003, 36, 8749-8760. [Full Text in PDF]


Honors and Awards


光华奖学金, 2021, USTC, Kang Ni (倪康)


第六届青年教师教学竞赛三等奖, 2018, USTC, Xiaodong Ye (叶晓东)


中国科大-苏州工业园区奖学金, 2017, USTC, Yating Gao (高亚婷)


郭永怀奖学金, 2014, USTC, Jinxian Yang (杨金先)


硕士研究生国家奖学金, 2014, USTC, Yating Gao (高亚婷)


Zhang Zongzhi Young Teacher Award, 2013, USTC


Dean Fellowship, 2004, USTC


Guanghua Prize, 2000, USTC


Guanghua Prize, 1999, USTC


Outstanding Student Scholarship, First Prize, 1998, USTC


Outstanding Student Scholarship, Second Prize, 1997, USTC


Fresh Scholarship, First Prize, 1996, USTC



Serves as a Reviewer for the Following Journals:


Macromolecules, ACS Macro Letters, Langmuir, Journal of Physical Chemistry B, ACS Appl. Mater. Interfaces, Biomacromolecules, Environ. Sci. Technol., Water Research, Soft Matter, Physical Chemistry Chemical Physics, Biomaterials Science, New Journal of Chemistry, European Polymer Journal, RSC Advances, Nanoscale, Journal of Polymer Science, Part A: Polymer Chemistry, Journal of Polymer Science, Part B: Polymer Physics, Macromolecular Chemistry and Physics, Colloid and Polymer Science, Chinese Journal of Chemical Physics