◆ 表观遗传云论坛：秀丽线虫里小调节性RNA的产生、功能与机制 [pdf]，【视频】
◆ Xiangyang Chen, Shouhong Guang, （2021） Genome manipulation using CRISPR/Cas9 technology in C. elegans, The 6th Chinese C. elegans Meeting, Workshop, Oct 17 [pdf]
[2024]
◆ Minjie Hong(#), Xiaotian Zhou(#), Chenming Zeng, Demin Xu, Ting Xu, Shimiao Liao, Ke Wang, Chengming Zhu, Ge Shan, Xinya Huang(*), Xiangyang Chen(*), Xuezhu Feng(*) & Shouhong Guang(*) (2024b) Nucleolar stress induces nucleolar stress body formation via the NOSR-1/NUMR-1 axis in Caenorhabditis elegans. Nature Communications, 2024 volume 15, Aug 23 https://doi.org/10.1038/s41467-024-51693-z [pdf]
◆ Xiangyang Chen(#), Ke Wang(#), Farees Ud Din Mufti(#), Demin Xu, Chengming Zhu, Xinya Huang, Chenming Zeng, Qile Jin, Xiaona Huang, Yong-hong Yan, Meng-qiu Dong, Xuezhu Feng(*), Yunyu Shi(*), Scott Kennedy(*) & Shouhong Guang(*) (2024a) Germ granule compartments coordinate specialized small RNA production. Nature Communications, 15, 5799 (2024). https://doi.org/10.1038/s41467-024-50027-3 [pdf]
◆ Ling Liu, Yifan Wu, Ke Liu, Mengdan Zhu, Shouhong Guang, Fengsong Wang, Xing Liu, Xuebiao Yao, Jiajia He(*), Chuanhai Fu(*) (2024) The absence of the ribosomal protein Rpl2702 elicits the MAPK-mTOR signaling to modulate mitochondrial morphology and functions. Redox Biol. 2024 Apr 29:73:103174. doi: 10.1016/j.redox.2024.103174. [pdf]
◆ Wei I Jiang, Henry De Belly, Bingying Wang, Andrew Wong, Minseo Kim, Fiona Oh, Jason DeGeorge, Xinya Huang, Shouhong Guang, Orion D Weiner, Dengke K Ma (2024) Early-life stress triggers long-lasting organismal resilience and longevity via tetraspanin Science Advance 2024 Jan 26;10(4):eadj3880. doi: 10.1126/sciadv.adj3880. Epub 2024 Jan 24. [pdf]
[2023]
◆ Ruofan Ding, Xudong Zou, Yangmei Qin, Lihai Gong, Hui Chen, Xuelian Ma, Shouhong Guang, Chen Yu, Gao Wang, Lei Li (2023) xQTLbiolinks: a comprehensive and scalable tool for integrative analysis of molecular QTLs. Brief Bioinform. 2023 Nov 22;25(1):bbad440. doi: 10.1093/bib/bbad440. [pdf]
◆ Pandey T, Kalluraya CA, Wang B, Xu T, Huang X, Shouhong Guang, Daugherty MD, Ma DK (*) (2023) Acquired stress resilience through bacteria-to-nematode interdomain horizontal gene transfer. EMBO J. (2023b) Nov 13:e114835. doi: 10.15252/embj.2023114835.
◆ Zhiwen Zhu(#), Dongdong Li, Zeran Jia, Wenhao Zhang, Yuling Chen, Ruixue Zhao, Yan-Ping Zhang, Wen-Hong Zhang, Haiteng Deng, Yinqing Li, Wei Li, Shouhong Guang, Guangshuo Ou(*) (2023) Global histone H2B degradation regulates insulin/IGF signaling-mediated nutrient stress. The EMBO Journal (2023a) Aug 29:e113328. doi: 10.15252/embj.2022113328. [pdf]
◆ Demin Xu(#), Xiangyang Chen(#), Yan Kuang, Minjie Hong, Ting Xu, Ke Wang, Xinya Huang, Chuanhai Fu, Ke Ruan, Chengming Zhu(*), Xuezhu Feng(*) and Shouhong Guang(*) (2023) rRNA intermediates coordinate the formation of nucleolar vacuoles in C. elegans. Cell Reports, 2023 Aug 1;42(8):112915. doi: 10.1016/j.celrep.2023.112915. [pdf]
◆ Xinhao Hou(#), Mingjing Xu(#), Chengming Zhu(#), Jianing Gao, Meili Li, Xiangyang Chen, Cheng Sun, Björn Nashan, Jianye Zang, Ying Zhou(*), Shouhong Guang(*), and Xuezhu Feng(*) (2022) Systematic characterization of chromodomain proteins reveals an H3K9me1/2 reader regulating aging in C. elegans. Nature Communications, 2023 Mar 6;14(1):1254. doi: 10.1038/s41467-023-36898-y. [pdf]
◆ Ting Xu，Shimiao Liao , Meng Huang, Chengming Zhu, Xiaona Huang, Qile Jin, Demin Xu, Chuanhai Fu, Xiangyang Chen(*), Xuezhu Feng(*) and Shouhong Guang(*) (2023) A ZTF-7/RPS-2 complex mediates the cold-warm response in C. elegans. PLoS Genetics, 2023 Feb 10;19(2):e1010628. doi: 10.1371/journal.pgen.1010628 [pdf]
[2022]
◆ Meng Huang(#), Minjie Hong(#), Chengming Zhu, Di Chen(*), Xiangyang Chen(*), Shouhong Guang(*), and Xuezhu Feng(*) (2022) H3K9me1/2 methylation limits the lifespan of daf-2 mutants in C. elegans. Elife. 2022 Sep 20;11:e74812. doi: 10.7554/eLife.74812. [pdf]
◆ Xuelian Ma(#), Shumin Cheng(#), Ruofan Ding, Zhaozhao Zhao, XuDong Zou, Shouhong Guang, Qixuan Wang, Huan Jing, Chen Yu, Ting Ni, Lei Li(*) (2022) ipaQTL-atlas: an atlas of intronic polyadenylation quantitative trait loci across human tissues. Nucleic Acids Research, 2022 Aug 31, https://doi.org/10.1093/nar/gkac736 [pdf]
◆ Xinhao Hou(#), Chengming Zhu, Mingjing Xu, Xiangyang Chen, Cheng Sun, Björn Nashana(*), Shouhong Guang(*), and Xuezhu Feng(*) (2022) The SNAPc complex mediates starvation-induced trans-splicing in C. elegans. Journal of Genetics and Genomics, 2022 Mar 10:S1673-8527(22)00076-5. doi: 10.1016/j.jgg.2022.02.024. [pdf]
[2021]
◆ Xiaoyang Wang(#), Chenming Zeng(#), Shanhui Liao(#), Zhongliang Zhu, Jiahai Zhang, Xiaoming Tu, Xuebiao Yao, Xuezhu Feng(*), Shouhong Guang(*), and Chao Xu(*) (2021) Molecular basis for PICS-mediated piRNA biogenesis and cell division. Nature Communications, 12, Article number: 5595 (2021) https://doi.org/10.1038/s41467-021-25896-7 [pdf]
◆ Zheng Xu(#), Jie Zhao, Minjie Hong, Chenming Zeng, Shouhong Guang(*), Yunyu Shi(*) （2021）Structural recognition of the mRNA 3’ UTR by PUF-8 restricts the lifespan of C. elegans. Nucleic Acids Research, Sept 3, 2021 https://doi.org/10.1093/nar/gkab754 【pdf】
◆ Shimiao Liao(#), Xiangyang Chen(#), Ting Xu(#), Qile Jin, Zongxiu Xu, Demin Xu, Xufei Zhou, Chengming Zhu(*), Shouhong Guang(*) and Xuezhu Feng(*) （2021）Antisense ribosomal siRNAs inhibit RNA polymerase I-directed transcription in C. elegans Nucleic Acids Research Aug 7, 2021 https://doi.org/10.1093/nar/gkab662 [pdf]
◆ Xinya Huang(#), Peng Cheng(#), Chenchun Weng, Zongxiu Xu, Chenming Zeng, Xiangyang Chen(*), Chengming Zhu(*), Shouhong Guang(*), and Xuezhu Feng(*) (2021) A chromodomain protein mediates heterochromatin-directed piRNA expression. PNAS, July 6, 2021 118 (27) e2103723118; https://doi.org/10.1073/pnas.2103723118 [pdf]
[2019]
◆ Chenming Zeng (#), Chenchun Weng (#), Xiaoyang Wang (#), Yong-Hong Yan (#), Wen-Jun Li, Demin Xu, Minjie Hong, Shanhui Liao, Meng-Qiu Dong, Xuezhu Feng (*), Chao Xu (*), and Shouhong Guang (*) (2019) Functional proteomics identifies a PICS complex required for piRNA maturation and chromosome segregation. Cell Reports Volume 27, ISSUE 12, P3561-3572.e3, June 18, 2019, DOI: https://doi.org/10.1016/j.celrep.2019.05.076 [pdf]
◆ Qi Yan (#), Chengming Zhu (#), Shouhong Guang (*) and Xuezhu Feng (*) (2019) The Functions of Non-coding RNAs in rRNA Regulation. Frontiers in Genetics April 05; Vol. 10, doi: 10.3389/fgene.2019.00290 [pdf]
◆ Chenchun Weng (#), Joanna Kosalka (#), Ahmet C. Berkyurek (#), Przemyslaw Stempor, Xuezhu Feng, Hui Mao, Chenming Zeng, Wen-Jun Li, Yong-Hong Yan, Meng-Qiu Dong, Natalia Rosalía Morero, Cecilia Zuliani, Orsolya Barabas, Julie Ahringer, Shouhong Guang (*), and Eric A. Miska (*) (2018) The USTC complex co-opts an ancient machinery to drive piRNA transcription in C. elegans. Genes & Development, Jan 1, 2019 [pdf]
[2018]
◆ Chengming Zhu (#), Qi Yan (#), Chenchun Weng , Xinhao Hou , Hui Mao , Dun Liu , Xuezhu Feng (*) , Shouhong Guang (*) (2018) Erroneous ribosomal RNAs promote the generation of antisense ribosomal siRNA. PNAS September 17, 2018 [pdf]
◆ Fei Xu (#), Xuezhu Feng (#), Xiangyang Chen, Chenchun Weng, Qi Yan, Ting Xu, Minjie Hong, and Shouhong Guang (*)（2018）A cytoplasmic Argonaute protein promotes the inheritance of RNAi. Cell Reports. 2018 Volume 23, Issue 8, p2482–2494, 22 May [pdf]
◆ Chen X (#*), Liao S (#), Huang X, Xu T, Feng X, Guang S (*). (2018) Targeted Chromosomal Rearrangements via a Combinatorial Use of CRISPR/Cas9 and Cre/LoxP Technologies in Caenorhabditis elegans. G3 (Bethesda). 2018 Jun 27. pii: g3.200473.2018. doi: 10.1534/g3.118.200473. [pdf]
◆ Fei Xu (#), Shouhong Guang (*), and Xuezhu Feng (*) (2018) Distinct nuclear and cytoplasmic machineries cooperatively promote the inheritance of RNAi in C. elegans. Biology of the Cell 2018 Aug 22. doi: 10.1111/boc.201800031 [pdf] (review)
◆ 陈向阳(*)，冯雪竹，光寿红(*) (2018) 靶向基因编辑技术在秀丽隐杆线虫中的应用，中国科学:生命科学 2018-03-07 doi/10.1360/N052017-00250. [pdf] (review)
[2017]
◆ Xufei Zhou, Xuezhu Feng, Hui Mao, Mu Li, Fei Xu, Kai Hu, and Shouhong Guang(2017) RdRP-synthesized antisense ribosomal siRNAs silence pre-rRNA via the nuclear RNAi pathway. Nature Structural & Molecular Biology 2017 Feb 6. doi: 10.1038/nsmb.3376. [pdf]
◆ Zhou X, Chen X, Wang Y, Feng X, Guang S. (2017) A new layer of rRNA regulation by small interference RNAs and the nuclear RNAi pathway. RNA Biol. 2017 Jun 22:0. doi: 10.1080/15476286.2017.1341034. [pdf] (review)
◆ 冯雪竹，光寿红 (2017) 细胞核内小干扰RNA介导的表观遗传和基因表达调控,中国科学:生命科学 2017：1-10 [pdf] (review)
[2016]
◆ Li G, Wu X, Qian W, Cai H, Sun X, Zhang W, Tan S, Wu Z, Qian P, Ding K, Lu X, Zhang X, Yan H, Song H, Guang S, Wu Q, Lobie PE, Shan G, Zhu T.(2016) CCAR1 5' UTR as a natural miRancer of miR-1254 overrides tamoxifen resistance. Cell Res. 2016 Jun;26(6):655-73. doi: 10.1038/cr.2016.32. [pdf]
◆ Xiangyang Chen, Xuezhu Feng (*) and Shouhong Guang (*) (2016) Targeted genome engineering in Caenorhabditis elegans. Cell & Bioscience 2016 6:60, DOI: 10.1186/s13578-016-0125-3 [pdf] (review)
[2015]
◆ Hui Mao, Chengming Zhu, Dandan Zong, Chenchun Weng, Xiangwei Yang, Hui Huang, Dun Liu, Xuezhu Feng, and Shouhong Guang (2015) The Nrde pathway mediates small RNA-directed histone H3 lysine 27 trimethylation in Caenorhabditis elegans. Current Biology 2015 Sep 21;25(18):2398-403. [pdf]
◆ Chen X, Li M, Feng X, Shouhong Guang (2015) Targeted Chromosomal Translocations and Essential Gene Knockout Using CRISPR/Cas9 Technology in Caenorhabditis elegans. Genetics 2015 Dec;201(4):1295-306 doi: 10.1534/genetics.115.181883. [pdf]
[2014]
◆ Xiangyang Chen, Fei Xu, Chengming Zhu, Jiaojiao Ji, Xufei Zhou, Xuezhu Feng, and Shouhong Guang (2014) Dual sgRNA-directed gene knockout using CRISPR/Cas9 technology in Caenorhabditis elegans. Scientific Reports 2014 Dec. 22;4:7581. [pdf]
◆ Zhou X, Xu F, Mao H, Ji J, Yin M, Feng X, and Shouhong Guang(2014) Nuclear RNAi Contributes to the Silencing of Off-Target Genes and Repetitive Sequences in Caenorhabditis elegans. Genetics 2014 May;197(1):121-32. [pdf]
[2013]
◆ Xuezhu Feng and Shouhong Guang(*) (2013) Small RNAs, RNAi and the Inheritance of Gene Silencing in Caenorhabditis elegans. Journal of Genetics and Genomics 2013，40:153-160 [pdf] (review)
◆ Feng X, Shouhong Guang (2013) Non-coding RNAs mediate the rearrangements of genomic DNA in ciliates. Sci China Life Sci. 2013 Oct;56(10):937-43. [pdf] (review)
◆ 冯雪竹，光寿红 (2013) 秀丽线虫细胞核内小干扰RNA调控基因表达的机制研究. 中国科学技术大学学报， 2013， 43(11)100-105. [pdf] (review)
[2012]
◆ Sam Guoping Gu, Julia Pak, Shouhong Guang, Jay M. Maniar, Scott Kennedy, and Andrew Fire, (2012) Amplification of siRNA in Caenorhabditis elegans generates a transgenerational sequence-targeted histone H3 lysine 9 methylation footprint. Nature Genetics 2012，44:157-164. [pdf]
[2011]
◆ Burkhart, K.B., Guang, S., Bochner, A.F., and Kennedy, S., (2011) A pre-mRNA–associating factor links endogenous siRNAs to chromatin regulation. PLoS Genetics2011 Aug;7(8):e1002249. [pdf]
[2010]
◆ Guang, S., Bochner, A.F., Pavelec, D.M., Burkhart, K.B., Burton, N., and Kennedy, S., (2010) Small regulatory RNAs inhibit RNA Polymerase II during the elongation phase of transcription. Nature, 2010，465:1097-1101. [pdf]
[2008]
◆ Guang, S., Bochner, A.F., Pavelec, D.M., Burkhart, K.B., Harding, S., Lachowiec, J., and Kennedy, S., (2008) An Argonaute transports siRNAs from the cytoplasm to the nucleus. Science 321:537-541 Research Article [pdf]
[2005]
◆ Guang, S., Felthauser, A., and Mertz, J. (2005) Binding of hnRNP L to the pre-mRNA processing enhancer (PPE) of herpes simplex virus’ thymidine kinase gene enhances both polyadenylation and nucleocytoplasmic export of intronless mRNAs. Mol. Cell. Biol. 25:6303-6313. [pdf]
◆ Guang, S. and Mertz, J.E. (2005) PPE-like elements from intronless genes play additional roles in mRNA biogenesis than do ones from intron-containing genes. Nucleic Acid Res. 33(7):2215-2226.